CLINICAL COMPUTATIONAL ANATOMY

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 临床计算解剖学(CCA)核心开发了表达人类和计算机都能解释的医学知识的工具。这些场馆包括体积、几何、结构和功能解剖学图集。核心是 致力于开发一份完整的大脑解剖图谱。完全开发的形式 该图谱将包括(1)基于高分辨率、多模式的体积脑图谱 活体正常受试者的核磁共振扫描；(2)解剖结构的专家标记 在这些扫描中成像；(3)这些标签与已建立的受控词汇表的链接 和解剖学的本体论；(4)和开发一种新的功能本体论， 描述了人体运动系统的功能神经解剖学，这与 在包括帕金森氏症在内的一组神经系统疾病中。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Clinical Computational Anatomy (CCA) core develops vehicles for expressing medical knowledge that can be interpreted by both humans and computers. These venues include volumetric, geometric, structural, and functional atlases of anatomy. The core is working to develop an integrated anatomic atlas of the brain. The fully developed form of this atlas will include (1) a volumetric brain atlas based on high resolution, multimodality MRI scans of a living, normal subject; (2) expert labeling of the anatomic structures imaged in these scans; (3) linkage of these labels to established, controlled vocabularies and ontologies of anatomy; (4) and development of a new functional ontology that describes the functional neuroanatomy of the human motor system, which is implicated in a group of neurologic disorders that includes Parkinson's disease.