THE ULTRASTRUCTURAL LOCATION OF MINERAL WITHIN STAPHYLOCOCCUS AUREUS

金黄色葡萄球菌内矿物质的超微结构位置

• 批准号: 8169652
• 负责人: PAUL ARMS PRICE
• 金额: $ 1.19万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8169652
• 关键词: Bacteria; Calcified; Cell Wall; Characteristics; Computer Retrieval of Information on Scientific Projects Database; Deposition; Exclusion; Funding; Grant; Incubated; Institution; Location; Minerals; Research; Research Personnel; Resources; Serum; Source; Staphylococcus aureus; Structure; United States National Institutes of Health; Work

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We have recently found that Staphylococcus aureus bacteria calcify rapidly when incubated in serum. The objective of the present study is to determine the ultrastructural location of the mineral deposited into these bacteria. Our working hypothesis is that the mineral will be deposited within the cell wall since this structure has size exclusion characteristics similar to those of other matrices that are calcified in serum.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 我们最近发现金黄色葡萄球菌在血清中培养时会迅速钙化。 本研究的目的是确定沉积到这些细菌中的矿物的超微结构位置。我们的工作假设是，矿物质将沉积在细胞壁内，因为这种结构具有类似于血清中钙化的其他基质的尺寸排阻特性。