ULTRASTRUCTURAL INVESTIGATION OF CYTONEMES AND THEIR CONTACT POINTS
ULTRASTRUCTURAL INVESTIGATION OF CYTONEMES AND THEIR CONTACT POINTS
批准号:
8169645
负责人:
THOMAS B. KORNBERG
金额:
$2.39万
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-04-01 至 2011-03-31
关键词:
CellsComputer Retrieval of Information on Scientific Projects DatabaseDevelopmentDrosophila genusElectron MicroscopyFundingGrantGrowth FactorGrowth Factor ReceptorsInstitutionInvestigationLarvaProcessResearchResearch PersonnelResourcesSignal TransductionSourceUnited States National Institutes of Healthimaginal disc
中文摘要
这个子项目是许多研究子项目中利用
资源由NIH/NCRR资助的中心拨款提供。子项目和
调查员(PI)可能从NIH的另一个来源获得了主要资金,
并因此可以在其他清晰的条目中表示。列出的机构是
该中心不一定是调查人员的机构。
细胞线是一种长的丝状突起,我们认为它用于发育过程中生长因子的长程信号传递。细胞线表达生长因子受体,并延伸到800um,然后与其在想象盘中的靶细胞接触。我们希望用电子显微镜来研究果蝇幼虫细胞线与靶细胞之间的接触点。
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
Cytonemes are long filopodial processes we believe are used in long range signaling of growth factors during development. Cytonemes express growth factor receptors and extend up to 800 um before contacting their target cells in the imaginal disk. We wish to use electron microscopy to study the contact points between cytonemes and target cells in Drosophila larvae.
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会议论文
Molecular Mechanisms in Development
-
批准号:9276924
-
项目类别:
-
资助金额:$24.74万
-
财政年份:2017
-
负责人:THOMAS B. KORNBERG
-
依托单位:
Molecular mechanisms in development
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批准号:10406603
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项目类别:
-
资助金额:$96.54万
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财政年份:2017
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负责人:THOMAS B. KORNBERG
-
依托单位:
Molecular Mechanisms in Development
-
批准号:9894651
-
项目类别:
-
资助金额:$91.99万
-
财政年份:2017
-
负责人:THOMAS B. KORNBERG
-
依托单位:
Molecular mechanisms in development
-
批准号:10621277
-
项目类别:
-
资助金额:$96.54万
-
财政年份:2017
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负责人:THOMAS B. KORNBERG
-
依托单位:
Tumor cytonemes, a new target for tumor suppression
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批准号:9247168
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项目类别:
-
资助金额:$20.68万
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财政年份:2016
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负责人:THOMAS B. KORNBERG
-
依托单位:
Hedgehog signaling and signal transduction
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批准号:8632014
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项目类别:
-
资助金额:$29.93万
-
财政年份:2014
-
负责人:THOMAS B. KORNBERG
-
依托单位:
Hedgehog signaling and signal transduction
-
批准号:9193088
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项目类别:
-
资助金额:$30.12万
-
财政年份:2014
-
负责人:THOMAS B. KORNBERG
-
依托单位:
Gene regulation and function in early embryos
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批准号:8840979
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项目类别:
-
资助金额:$30.08万
-
财政年份:2014
-
负责人:THOMAS B. KORNBERG
-
依托单位:
Hedgehog signaling and signal transduction
-
批准号:8987583
-
项目类别:
-
资助金额:$30.12万
-
财政年份:2014
-
负责人:THOMAS B. KORNBERG
-
依托单位:
Gene regulation and function in early embryos
-
批准号:8630961
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项目类别:
-
资助金额:$29.98万
-
财政年份:2014
-
负责人:THOMAS B. KORNBERG
-
依托单位:
Gene regulation and function in early embryos
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批准号:8998035
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项目类别:
-
资助金额:$30.12万
-
财政年份:2014
-
负责人:THOMAS B. KORNBERG
-
依托单位:
Hedgehog signaling and signal transduction
-
批准号:8791112
-
项目类别:
-
资助金额:$30.07万
-
财政年份:2014
-
负责人:THOMAS B. KORNBERG
-
依托单位:
Gene regulation and function in early embryos
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批准号:9198245
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项目类别:
-
资助金额:$30.12万
-
财政年份:2014
-
负责人:THOMAS B. KORNBERG
-
依托单位:
MOLECULAR MECHANISMS IN DEVELOPMENT
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批准号:7987021
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项目类别:
-
资助金额:$11.68万
-
财政年份:2009
-
负责人:THOMAS B. KORNBERG
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依托单位:
STUDIES OF PROTEINS THAT TRANDUCE HEDGEHOG SIGNALING
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批准号:7723519
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项目类别:
-
资助金额:$2.87万
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财政年份:2008
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负责人:THOMAS B. KORNBERG
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依托单位:
THE DROSOPHILA DORSAL AIR SACS, A MODEL SYSTEM FOR LUNG DEVELOPMENT
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批准号:7315420
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项目类别:
-
资助金额:$38.5万
-
财政年份:2007
-
负责人:THOMAS B. KORNBERG
-
依托单位:
THE DROSOPHILA DORSAL AIR SACS, A MODEL SYSTEM FOR LUNG DEVELOPMENT
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批准号:7868006
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项目类别:
-
资助金额:$38.63万
-
财政年份:2007
-
负责人:THOMAS B. KORNBERG
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依托单位:
THE DROSOPHILA DORSAL AIR SACS, A MODEL SYSTEM FOR LUNG DEVELOPMENT
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批准号:7629146
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项目类别:
-
资助金额:$38.63万
-
财政年份:2007
-
负责人:THOMAS B. KORNBERG
-
依托单位:
THE DROSOPHILA DORSAL AIR SACS, A MODEL SYSTEM FOR LUNG DEVELOPMENT
-
批准号:7499671
-
项目类别:
-
资助金额:$38.63万
-
财政年份:2007
-
负责人:THOMAS B. KORNBERG
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依托单位:
HEDGEHOG SIGNALING IN DEVELOPMENT AND DISEASE
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批准号:7612767
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项目类别:
-
资助金额:$27.85万
-
财政年份:2006
-
负责人:THOMAS B. KORNBERG
-
依托单位: