TRAINING IN FOURIER TRANSFORM ION CYCLOTRON RESONANCE MASS SPECTROMETRY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 该计划的目标之一是培养新的研究生和专业科学研究人员掌握新技术。我们重点研究的一种这样的技术是傅里叶变换质谱仪。 自2009年1月Peter O‘Connor博士离职成为英国考文垂华威大学化学系终身教授以来，程林博士一直负责FTMS方面的培训以及基于FTMS的研究项目。他现在是波士顿大学医学院生物化学系的研究助理教授，以及资源的助理主任。 2009年11月，FTMS研究小组的研究生康斯坦丁·艾兹科夫为自己的博士论文辩护，目前仍在MSR担任糖生物信息学博士后助理。 崔卫东博士曾是博士后，2009年5月离开华盛顿大学，在圣路易斯的华盛顿大学担任研究员一职。 2009年9月，纪玉环作为研究生加入FTMS小组，与科恩博士在医学系的小组合作，在氧化应激下研究人类H-ras修饰。2009年12月，黄益群博士以博士后身份加入FTMS小组，从事多肽和碳水化合物ECD的机理研究。 2010年1月，新到货的12T Bruker SolariX FT-ICR仪器通过高端共享仪器赠款获得，并于2010年1月通过了所有规格的认证。从那时起，资源中心的几名博士后研究助理和FTMS小组的高级研究生都接受了适当的培训，以便将这一新工具用于各种研究项目。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. One of the objectives of this program is to train new graduate students and professional scientific researchers in new techniques. One such technique which we have focused on is Fourier transform mass spectrometry. Since the departure of Dr. Peter O'Connor in Jan 2009 to become a tenured full professor in the Department of Chemistry at the University of Warwick, Coventry, England, Dr. Cheng Lin has assumed responsibility for training in FTMS, and FTMS-based research projects. He is now a research assistant professor in the Department of Biochemistry at Boston University School of Medicine, and the Assistant Director of the Resource. A graduate student from the FTMS research group, Konstantine Aizikov, defended his Ph. D. thesis in November 2009, and remains at the MSR as a postdoctoral associate working on glyco-bioinformatics. A former postdoc, Dr. Weidong Cui left in May 2009 to take a staff scientist position at Washington University in St. Louis. In September 2009, Yuhuan Ji joined the FTMS group as a graduate student, working on human H-ras modifications under oxidative stress, in collaboration with Dr. Cohen's group in the Department of Medicine. In December 2009, Dr. Yiqun Huang joined the FTMS group as a postdoctoral fellow, taking on the mechanistic studies of ECD of peptides and carbohydrates. In January 2010, the newly arrived 12 T Bruker solariX FT-ICR instrument, acquired through a high-end shared instrument grant, was certified to meet all specs in January 2010. Since then, several postdoctoral research associates of the Resource and senior graduate students from the FTMS group have been properly trained to use this new instrument for a diversity of research projects.