2011 Gradient Sensing and Directed Cell Migration Gordon Research Conference

2011 梯度传感和定向细胞迁移戈登研究会议

• 批准号: 8128064
• 负责人: TOBIAS MEYER
• 金额: $ 1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8128064
• 关键词: Address; Allergic Disease; Animal Model; Area; Arthritis; Asthma; Basic Science; Biological Models; Biomedical Engineering; Cardiovascular Diseases; Cell Polarity; Cells; Chemotaxis; Collaborations; Complex; Cytoskeleton; Development; Dictyostelium; Discipline; Disease; Environment; Goals; Growth Cones; Health; Human; Immigration; Immune; Immunologic Deficiency Syndromes; Inflammation; Inflammatory; Intention; Leukocyte Trafficking; Link; Malignant Neoplasms; Modeling; Neoplasm Metastasis; Nerve Degeneration; Neurons; Pathogenesis; Pathway interactions; Public Health; Research; Research Personnel; Rheumatism; Scholarship; Scientist; Signal Transduction; Switzerland; System; Underrepresented Minority; Woman; Wound Healing; abstracting; axonal guidance; cell motility; human disease; improved; meetings; neuron development; novel; novel strategies; novel therapeutics; polarized cell; posters; programs; symposium; therapeutic development; trafficking

DESCRIPTION (provided by applicant): The 2011 Gordon Research Conference (GRC) on Gradient Sensing and Directed Cell Migration will be held from June 5-10, 2011 at Les Diablerets Conference Center in Les Diablerets, Switzerland. This conference will follow three successful Gordon Conferences in the field of chemotaxis research, which have been held every two years since 2005. The conference addresses the basic research question of how cells polarize and migrate directionally in diverse systems by discussing development, neuronal path finding, leukocyte trafficking, wound healing, tissue repair, and cancer. The conference is also relevant to the development of therapeutics aimed at disorders where cell migration is central to disease pathogenesis including: cardiovascular diseases, rheumatic and allergic diseases, asthma, and cancer. The program highlights the commonality of mechanisms that regulate directed cell migration in the context of diverse systems and the implications of these common pathways to the development of disease. The conference will emphasize new concepts about the basic mechanisms that regulate gradient sensing and directed cell migration, and will explore links between cell migration during development, wound healing, immune cell trafficking, and cancer. Nine discussion sessions are planned: (1) Directed Cell Migration in Cancer, (2) Neuronal Polarity and Growth Cone Guidance (3) Directed Cell Migration in Animal Model Systems, (4) Collective Migration in Development and Wound Healing, (5) Inflammation and Leukocyte Trafficking, (6) Cell Signaling in Chemotaxis, (7) Cell Polarity and the Cytoskeleton in Directed Cell Migration, (8) Quantitative Modeling of Directed Cell Migration. The combination of speakers and topics has been selected with the specific intention of stimulating new ideas and collaborations in the field of chemotaxis research. The session speakers, selected from a variety of fields, will emphasize novel, unpublished results directly related to gradient sensing and directed cell migration. Young investigators will be encouraged to present and discuss their findings in a supportive environment through the invitation of up to 20 additional speakers, selected from submitted abstracts, and by participation in the posters sessions. Scholarships will be offered to encourage the attendance of young scientists, women and underrepresented minorities. Throughout the conference, interactions between senior and young investigators will be promoted in both formal and informal settings. Support of this program will assure that the meeting will be successful and will provide much needed sponsorship for outstanding young scientists who wish to attend. PUBLIC HEALTH RELEVANCE: The Gordon Research Conference on Gradient Sensing and Directed Cell Migration addresses the fundamental mechanisms that regulate directed cell migration and axonal path finding. This area of research has substantial importance to the development of new therapeutics to treat a diverse array of human diseases including cancer, cardiovascular disease, arthritis, asthma and neuronal degeneration. This conference will bring together experts who study directed cell migration mechanisms in simple and complex systems in order to stimulate new ideas and advance our abilities to improve public health.

描述（由申请人提供）：2011年梯度传感和定向细胞迁移戈登研究会议（GRC）将于2011年6月5日至10日在瑞士Les Diablerets会议中心举行。本次会议将继自2005年以来每两年成功举办三届趋化性研究领域的戈登会议之后。会议通过讨论发育、神经元路径寻找、白细胞运输、伤口愈合、组织修复和癌症，解决了细胞如何在不同系统中极化和定向迁移的基本研究问题。该会议还涉及针对细胞迁移对疾病发病机制至关重要的疾病的治疗方法的发展，包括：心血管疾病、风湿病和过敏性疾病、哮喘和癌症。该计划强调了在不同系统背景下调节定向细胞迁移的机制的共性，以及这些共同途径对疾病发展的影响。会议将强调关于调节梯度传感和定向细胞迁移的基本机制的新概念，并将探讨发育过程中细胞迁移、伤口愈合、免疫细胞运输和癌症之间的联系。计划有九场讨论会：(1)癌症中的定向细胞迁移，(2)神经元极性和生长锥引导(3)动物模型系统中的定向细胞迁移，(4)发育和伤口愈合中的集体迁移，(5)炎症和白细胞运输，(6)趋化性中的细胞信号传导，(7)定向细胞迁移中的细胞极性和细胞骨架，(8)定向细胞迁移的定量建模。选择演讲者和主题的组合是为了在趋化性研究领域激发新的想法和合作。会议发言人，选择从各个领域，将强调新的，未发表的结果直接相关的梯度传感和定向细胞迁移。青年研究人员将被鼓励在一个支持性的环境中展示和讨论他们的发现，通过邀请多达20个额外的演讲者，从提交的摘要中选择，并参加海报会议。将提供奖学金，鼓励年轻科学家、女性和未被充分代表的少数民族参加。在整个会议期间，将在正式和非正式环境中促进高级和年轻研究人员之间的互动。这个项目的支持将确保会议的成功，并将为希望参加会议的优秀青年科学家提供急需的赞助。