54th Annual Thomas L. Petty Aspen Lung Conference: COPD and Lung Cancer: Common P

描述(申请人提供)：第54届Thomas L.Petty Aspen肺部年会的主题是“慢性阻塞性肺病和肺癌：共同的发病机制和共同的临床挑战”。重点将放在基础科学、翻译科学和临床科学的整合上。将探讨COPD和肺癌的临床影响，以及与香烟烟雾流行有关的最常见的并发症，该计划将确定每种疾病发病机制中的共同和独特的机制事件，以12个“最新”报告为基础，主题会议将讨论这两个疾病的遗传易感性和流行病学、呼吸干细胞生物学、衰老的作用、基因突变、表观遗传学、全身炎症、新的靶向治疗以及疾病修改或预防干预措施。这一重点与NHLBI和NCI最近共同努力解决COPD和肺癌的机制是一致的。会议纪要将由哈佛大学医学教授、波士顿布里格姆妇女医院肺科学和危重护理医学部医学博士Bartolome Celli介绍。会议的主要目的是：1)为基础和临床研究人员提供一个国际论坛，交流与两种主要的相互关联的肺部疾病有关的想法；2)满足公认的参与这一领域的需求，这个领域的知识每五年翻一番；3)为与会者提供一个机会，通过与国内和国际公认的临床医生和研究人员的审查和讨论，深入关注一个主题；以及4)推动肺部和重症护理医学的进一步研究。

DESCRIPTION (provided by applicant): The theme of the 54th Annual Thomas L. Petty Aspen Lung Conference is "COPD and Lung Cancer: Common Pathogenesis Shared Clinical Challenges". The emphasis will be on the integration of basic, translational and clinical sciences. The clinical impact of COPD and lung cancer, the most frequent complications related to the cigarette smoke epidemic will be explored, and the program will identify shared and unique mechanistic events in each disease's pathogenesis Anchored by twelve "state-of-the-art" presentations, thematic sessions will address in both disorders genetic susceptibility and epidemiology, respiratory stem cell biology, role of senescence, genetic mutations, epigenetics, systemic inflammation, novel targeted therapies, and disease modifying or preventive interventions. This focus is in line with the recent joint effort by the NHLBI and NCI to address the mechanism underlying both COPD and lung cancer. The Conference Summary will be presented by Bartolome Celli, M.D., Professor of Medicine, Harvard University, Division of Pulmonary Sciences and Critical Care Medicine, Brigham and Women's Hospital, Boston. The main objectives of the conference are to 1) provide an international forum for basic and clinical researchers to exchange ideas relating to two major interrelated lung diseases; 2) fill a recognized need for participation in a field where knowledge is doubling every five years; 3) provide an opportunity for participants to focus in depth on a single topic by review and discussion with nationally and internationally recognized clinicians and researchers; and 4) provide an impetus to further research in pulmonary and critical care medicine