54th Annual Thomas L. Petty Aspen Lung Conference: COPD and Lung Cancer: Common P

简介（由申请人提供）：第54届Thomas L. Petty Aspen年度肺病会议的主题是“COPD和肺癌：共同的发病机制和临床挑战”。重点将放在基础科学、转化科学和临床科学的整合上。将探讨慢性阻塞性肺病和肺癌的临床影响，以及与吸烟流行相关的最常见并发症，该计划将确定每种疾病发病机制中共享和独特的机制事件。由12个“最先进”的演讲为基础，专题会议将讨论疾病遗传易感性和流行病学，呼吸干细胞生物学，衰老的作用，基因突变，表观遗传学，全身性炎症，新的靶向治疗，疾病修饰或预防干预。这一重点与最近NHLBI和NCI共同努力解决COPD和肺癌的潜在机制是一致的。会议总结将由Bartolome Celli，医学博士，哈佛大学肺科学和危重病医学系教授，波士顿布莱根妇女医院。会议的主要目标是1)为基础和临床研究人员提供一个国际论坛，以交流有关两种主要相互关联的肺部疾病的想法；2)在知识每五年翻一番的领域满足公认的参与需求；3)通过与国内和国际公认的临床医生和研究人员的回顾和讨论，为参与者提供深入关注单个主题的机会；4)为肺部和重症医学的进一步研究提供了动力

DESCRIPTION (provided by applicant): The theme of the 54th Annual Thomas L. Petty Aspen Lung Conference is "COPD and Lung Cancer: Common Pathogenesis Shared Clinical Challenges". The emphasis will be on the integration of basic, translational and clinical sciences. The clinical impact of COPD and lung cancer, the most frequent complications related to the cigarette smoke epidemic will be explored, and the program will identify shared and unique mechanistic events in each disease's pathogenesis Anchored by twelve "state-of-the-art" presentations, thematic sessions will address in both disorders genetic susceptibility and epidemiology, respiratory stem cell biology, role of senescence, genetic mutations, epigenetics, systemic inflammation, novel targeted therapies, and disease modifying or preventive interventions. This focus is in line with the recent joint effort by the NHLBI and NCI to address the mechanism underlying both COPD and lung cancer. The Conference Summary will be presented by Bartolome Celli, M.D., Professor of Medicine, Harvard University, Division of Pulmonary Sciences and Critical Care Medicine, Brigham and Women's Hospital, Boston. The main objectives of the conference are to 1) provide an international forum for basic and clinical researchers to exchange ideas relating to two major interrelated lung diseases; 2) fill a recognized need for participation in a field where knowledge is doubling every five years; 3) provide an opportunity for participants to focus in depth on a single topic by review and discussion with nationally and internationally recognized clinicians and researchers; and 4) provide an impetus to further research in pulmonary and critical care medicine