2011 Gordon Research Conference on Nitric Oxide

描述(申请人提供)：戈登一氧化氮(NO)研究会议旨在为化学家、生物学家、临床医生和其他科学家提供关于NO生成系统的基本结构/功能关系的最新知识，以及NO作为生理学和病理生理学中的信号和效应分子的生物学知识。本次研究会议每两年举行一次，下一次会议将于2011年2月13日至18日在加利福尼亚州文图拉的Four Points Sheraton/Holiday Inn Express举行。预计将有来自学术界、政府和工业界的约150名代表参加这次会议。请拨资金以支付与会者(即来自美国和国外的演讲者/讨论负责人，以及杰出的研究生/博士后候选人和其他从事非生物学领域的初级科学家)的旅费和会议注册费。选择演讲者是为了解决悬而未决的问题，覆盖该领域正在出现的新领域，并与高级和初级调查人员平衡该计划。会议将包括细菌、植物和哺乳动物的NO产生和传感系统的并列比较；它们参与调节底物利用、中间代谢和应对缺氧的机制；以及涉及的信号转导途径。此外，还将介绍新的治疗途径，重点是了解所涉及的分子过程。卡尔·内森诚挚地同意发表主旨演讲。虽然本次会议没有集中讨论传染病问题，但他将在发言中谈到在其他情况下个别会议所涉及的许多机械方面的问题，使会议更加突出，并为与会人员提供独特的学习机会。此外，从提交给会议的摘要中挑选了两个突出的特色和主持的海报会议，一个是关于“当前争议和最新发现”的特别会议，另一个是“热点”会议，该会议鼓励新的或老牌调查人员在最后一刻提交令人兴奋的调查结果，最终向几名初级调查人员颁发奖项。这次会议的主要优势是有机会在高度集中但非正式的智力刺激气氛中进行跨学科互动。戈登关于NO的会议在提供指导和探索这一重要的基础和翻译研究领域的新前景方面发挥了至关重要的作用。

DESCRIPTION (provided by applicant): The Gordon Research Conference on Nitric Oxide (NO) is designed to provide chemists, biologists, clinicians and other scientists with state-of-the-art knowledge on the basic structure/function relationships of NO generating systems, and the biology of NO as a signaling and effector molecule in physiology and pathophysiology. This research conference is held every two years and the next conference will take place at the Four Points Sheraton/Holiday Inn Express in Ventura, CA on Feb 13-18, 2011. Approximately 150 participants from academia, government and industry are expected to attend this conference. Funds are requested to support travel costs and conference registration fees for participants (i.e. speakers/discussion leaders from the United States and abroad and for exceptional graduate students/post-doctoral candidates and other junior scientists working in the field of NO biology). The speakers have been selected to address unresolved questions and cover emerging new areas in the field and to balance the program with senior and junior investigators. Sessions will include a side-by-side comparison of bacterial, plant and mammalian NO producing and sensing systems; their involvement in regulating substrate utilization, intermediary metabolism, and mechanisms of coping with oxygen shortage; and the signal transduction pathways involved. In addition, novel therapeutic avenues will be covered with an emphasis on understanding the molecular processes involved. Carl Nathan has kindly agreed to present the Keynote Lecture. Although this meeting does not focus on infectious disease, he will touch in his presentation on many of the mechanistic aspects covered in individual sessions in other contexts, adding distinction to the meeting and offering a unique learning opportunity for those in attendance. In addition, there are two prominently featured and moderated poster sessions selected from abstracts submitted to the meeting, a special session on "Current Controversies and Late-Breaking Findings" and a "Hot Topics" session that encourages last-minute submissions of exciting findings from new or established investigators culminating in awards given to several of the junior investigators. The main strength of this meeting is the opportunity for cross-disciplinary interactions in a highly focused, yet informal intellectually stimulating atmosphere. The Gordon Conference on NO plays an essential role in providing guidance and exploring new vistas in this important field of basic and translational research.