Brain, Behavior and Immunity in Health and Disease

描述（由申请人提供）：本R13会议提案要求支持继续在2012年6月6日至9日在加州圣地亚哥举行的第19届心理神经免疫学研究学会（PNIRS）年会上为20 - 25名博士前和博士后学员提供年度培训和指导计划。对行为和神经免疫相互作用的基础科学方面及其对疾病预防和治疗的转化相关性感兴趣的初级科学家进行高级跨学科培训的机会通常在大学一级受到限制。自1999年以来，PNIRS会议得到了NIH的支持，为270多名研究员提供了正式的教学指导和建设性的职业指导。主要目标是创造教学机会，并在受训者职业生涯的形成阶段提供支持性指导，以提高他们的研究潜力和轨迹 为了成功PNIRS是主要的专业组织，代表了这些类型的调查所涉及的许多不同的科学学科。PNIRS拥有约332名成员，其中约40%处于职业生涯早期。PNIRS培训委员会监督协会对指导计划的承诺，并确保其质量。实习学者的选择，包括五个多样性的学员，是基于一个公开的竞争，并通过卓越的研究和职业前途决定。该计划的影响是由以前获奖者的生产力和他们的科学成就证明。除了接触到快速发展的科学和口头会议和由领先的科学家提供的主题演讲，实习学者参加教育短期课程，高级教师-实习生指导座谈会，初级教师和实习生研讨会，以及与NIH计划工作人员的圆桌讨论。学员提交的摘要也会被审查，以确定是否有可能被纳入由竞争性摘要提交和紧接在每个海报会议之前的“数据闪电战”会议开发的主题口头会议。最后，举办学员晚宴，进一步培养建立持久的合作和科学关系。这项培训和指导计划与国家癌症研究所（NCI）和其他NIH研究所的使命一致，即增加年轻科学家的数量，研究将生活方式和心理因素与促进健康联系起来的生物行为途径，并破译宿主因素在疾病病理生理学中的作用。心理神经免疫学（PNI）相关研究表明，心理因素和生活方式会影响免疫能力，影响疾病易感性。PNI的生物行为研究结果与广泛的疾病密切相关，有助于解释发病率和死亡率以及生活质量的变化。PNI方法还提供了独特的评估策略和结果措施，用于评估非传统和补充医学方法的疗效。基于对脑免疫相互作用的丰富理解，PNI还为免疫系统对神经精神疾病的潜在贡献提供了新的见解。 公共卫生相关性：这个R13会议奖将使20 - 25最有前途的前和博士后研究科学家参加即将举行的2012年心理神经免疫学研究学会会议将于6月6日至9日在圣地亚哥，加利福尼亚州。这些学者获奖者将有机会传播他们的发现，并参加特殊的培训和指导活动，这将提高他们在与美国国立卫生研究院的使命密切相关的跨学科基础科学和转化研究中取得成功的可能性。

DESCRIPTION (provided by applicant): This R13 meeting proposal requests support to continue an annual training and mentoring program for 20 - 25 pre- and postdoctoral trainees at the 19th annual meeting of the PsychoNeuroImmunology Research Society (PNIRS), June 6-9, 2012, to be held in San Diego, California. Opportunities for advanced, interdisciplinary training of junior scientists interested in the basic science aspects of behavioral and neuroimmune interactions and their translational relevance for disease prevention and treatment are often limited at the university level. Since 1999, the PNIRS meeting has received NIH support to provide formal didactic instruction and constructive career guidance for over 270 fellows. The primary goal is to create pedagogical opportunities and offer supportive mentoring at this formative stage in the trainee's career in order to enhance their research potential and trajectory for success. The PNIRS is the primary professional organization representing the many diverse scientific disciplines involved in these types of inquiry. The PNIRS has approximately 332 members, including approximately 40% early in their career. The PNIRS Training Committee oversees the Society's commitment to the mentoring program and ensures its quality. Selection of the Trainee Scholars, including five diversity trainees, is based upon an open competition, and is determined by research excellence and career promise. The impact of this program is evidenced by the productivity of previous awardees and their scientific successes. In addition to the exposure to a rapidly evolving science and oral sessions and keynote talks offered by leading scientists, trainee scholars participate in an Educational Short Course, a Senior Faculty- Trainee Mentoring Colloquium, Junior Faculty and Trainee workshop, and roundtable discussions with NIH program staff. Trainee abstract submissions are also reviewed for potential inclusion in thematic oral sessions developed from competitive abstract submissions and the "Data Blitz" sessions that immediately precede each poster session. Finally, a trainee dinner is held to further nurture the establishment of enduring collaborative and scientific relationships. This training and mentoring program is congruent with the mission of the National Cancer Institute (NCI) and other NIH institutes to increase the number of young scientists investigating biobehavioral pathways linking lifestyle and psychological factors to the promotion of health and to deciphering the role of host factors in the pathophysiology of disease. Psychoneuroimmunology (PNI) related research has shown that psychological factors and lifestyle can impact immune competence and influence disease susceptibility. PNI biobehavioral research findings are germane to a wide range of diseases and help to account for variations in morbidity and mortality as well as quality of life. PNI methodologies also offer unique assessment strategies and outcome measures for evaluating the efficacy of nontraditional and complementary medicine approaches. Based on an enriched understanding of brain-immune interactions, PNI has also provided novel insights into the potential contributions of the immune system to neuropsychiatric disorders. PUBLIC HEALTH RELEVANCE: This R13 meeting award will enable 20 - 25 of the most promising pre- and postdoctoral research scientists to participate in the upcoming 2012 PsychoNeuroImmunology Research Society meeting to be held June 6 - 9 in San Diego, CA. These Scholar Awardees will have the opportunity to disseminate their findings and participate in special training and mentoring activities that will improve their likelihood of having a successful career in interdisciplinary basic science and translational research germane to the mission of the National Institutes of Health.