Development of a Miniature Plasma Brush for Dental Clinical Applications
Development of a Miniature Plasma Brush for Dental Clinical Applications
批准号:
8286069
负责人:
Meng Chen
金额:
$55.87万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-04-01 至 2014-06-30
关键词:
AdhesivesAdverse effectsAirAnimalsBacteriaBacterial InfectionsBiologicalBody TemperatureBoxingCaries preventionCitiesClinicalClinical TrialsCollagen FibrilDentalDental Cavity PreparationDental ClinicsDental EnamelDental TechnologyDental cariesDentinDentistryDevelopmentDevicesDisinfectionElectromagneticsElectronicsEngineeringEnsureEnvironmentEvaluationExcisionFailureFundingGasesGoalsHuman bodyIn VitroKansasLasersLeadLifeLiquid substanceLongevityMechanicsMedicalMissouriNatureOralPenetrationPhasePlant ResinsPlasmaPreparationProceduresProcessQuality ControlRecurrenceRegulationResourcesSafetySchool DentistryStreptococcus mutansSurfaceSystemTechniquesTemperatureTimeTissuesTooth FracturesTooth structureUniversitiesWater fluoridationWorkchemical bondclinical applicationcommercializationcomposite restorationdensitydesignevaluation/testingfightingimprovedinnovationinterfacialkillingsmicroleakagemillimeternoveloperationpreventprogramsprototypepublic health relevancerestorative dentistrytooth surfaceuser-friendly
中文摘要
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英文摘要
DESCRIPTION (provided by applicant): The main objective of this project is to develop a miniature atmospheric cold plasma brush (m- ACPB) for dental clinical applications. The innovation of this project is the utilization of the recently developed novel non-thermal atmospheric plasma technology for dental treatment to prevent tooth decay and improve the durability and longevity of dental composite restoration. Non-thermal atmospheric plasma is a gaseous medium that is chemically reactive and has the capability to penetrate irregular cavities and fissures and kill bacteria. Furthermore, plasma species can spread up to a few millimeters into a fluid. This feature make non-thermal plasmas extremely suitable to treat, clean, disinfect tooth decay, and fluorinate enamel in a wet oral environment. Plasma treatment of tooth decays or dental surfaces allows us to avoid contamination, actively fight bacterial infections, effectively fluorinate the tooth surfaces, offer additional cleaning to the decayed matters, and prepare/engineer the dental surface for strong and durable bonding to adhesive and sealant materials with a simple plasma treatment process. Such dental clinical applications will be achieved through the development of an m-ACPB that is suitable for dental clinical use.
PUBLIC HEALTH RELEVANCE: Nanova, Inc. is developing a miniature atmospheric cold plasma brush (m-ACPB) for dental clinical applications. The innovation of this project is the utilization of the recently developed novel non-thermal atmospheric plasma technology for dental treatment to prevent tooth decay and improve the durability and longevity of dental composite restoration, and could become a high-impact innovation in dentistry.
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DOI:
10.31487/j.dobcr.2021.02.05
发表时间:
2021
期刊:
Dental Oral Biology and Craniofacial Research
影响因子:
--
作者:
[Hong, Qing, Dong, Xiaoqing, Chen, Meng, Sun, Hongmin, Hong, Liang, Wang, Yong, Yu, Qingsong]
通讯作者:
Yu, Qingsong
DOI:
10.1111/eos.12052
发表时间:
2013-08
期刊:
European journal of oral sciences
影响因子:
1.9
作者:
[Dong X, Ritts AC, Staller C, Yu Q, Chen M, Wang Y]
通讯作者:
Wang Y
DOI:
10.1371/journal.pone.0274523
发表时间:
2022
期刊:
PloS one
影响因子:
3.7
作者:
[]
通讯作者:
Plasma treatment of dentin surfaces for improving self-etching adhesive/dentin interface bonding.
牙本质表面的血浆处理,以改善自蚀刻粘合剂/牙本质接口键合。
DOI:
10.1016/j.cpme.2015.05.002
发表时间:
2015-06-01
期刊:
Clinical plasma medicine
影响因子:
--
作者:
[Dong X, Li H, Chen M, Wang Y, Yu Q]
通讯作者:
Yu Q
DOI:
--
发表时间:
2014-04
期刊:
American journal of dentistry
影响因子:
1.4
作者:
[A. Blumhagen;Prashant Singh;A. Mustapha;Meng Chen;Yong Wang;Qingsong Yu]
通讯作者:
A. Blumhagen;Prashant Singh;A. Mustapha;Meng Chen;Yong Wang;Qingsong Yu
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