UAB Nutrition Obesity Research Center (NORC)

UAB 营养肥胖研究中心 (NORC)

• 批准号: 8385981
• 负责人: DAVID B ALLISON
• 金额: $ 112.94万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-06-01 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8385981
• 关键词: Adult; Aging; Animal Model; Area; Back; Behavioral; Biological; Biometry; Body Composition; Body fat; Caloric Restriction; Cancer Grant Supplements (P30); Childhood; Clinical; Clinical Research; Comprehensive Cancer Center; Development; Diabetes Mellitus; Disease; Education; Endocrinology; Environment; Environmental Risk Factor; Epidemiology; Exercise Physiology; Fostering; Funding; Genetic; Genomics; Geriatrics; Grant; Guidelines; Health; Industry; Instruction; Intake; Interdisciplinary Study; K-Series Research Career Programs; Knowledge; Leadership; Literature; Longevity; Medical Students; Meta-Analysis; Metabolic; Metabolism; Misinformation; Mission; Molecular Biology; Names; National Institute of Diabetes and Digestive and Kidney Diseases; Nutritional; Obesity; Output; Pathology; Patient Care; Pediatric Surgical Procedures; Peer Review; Physicians; Physiology; Play; Population; Positioning Attribute; Production; Psychology; Public Health; Public Health Schools; Publications; Quality of life; Randomized Controlled Trials; Recruitment Activity; Research; Research Infrastructure; Research Personnel; Review Literature; Role; Science; Scientist; Series; Strategic Planning; Superstitions; Technology; Training; Translational Research; United States National Institutes of Health; Writing; base; cost effective; health disparity; medical schools; member; minority health; multidisciplinary; muscle metabolism; nutrition; profession allied to medicine; programs; statistics; success; symposium; trait

We request renewed funding to continue the documented success achieved by UAB's Nutrition Obesity Research Center (NORC) in its first two funding cycles. Inaugurated with NIH funding in 2000, our NORC fosters multidisciplinary, collaborative basic clinical and translational nutrition and obesity research. Since it was first funded, the NORC's research base has grown substantially. At inception (2000), we had 60 members; this number increased 70% to 102 members in 2006 at our last renewal and another 31% to 134 members in 2011. In 2000, our members held as Pis 15 R01s or K-awards that were clearly related to nutrition or obesity; this number increased 93% to 29 such grants active in 2006 and another 17% to 34 (including ROD grants) active in 2011 (as of this writing). UAB's NORC has directly helped to recruit at least a dozen new and established obesity and nutrition investigators in the past funding cycle. Our publication output has steadily increased in absolute numbers and as a proportion of the world's literature on obesity and nutrition. The impact of NORC publications as judged by citation counts consistently exceeds the norm for peer-reviewed literature on obesity and nutrition. Our NORC leadership oversees two NIH-funded T32 training grants for obesity research, an industry-sponsored obesity training grant, and a series of national nutrition and obesity-related conferences. Our NORC funds at least four P/F studies per year, a Named New Investigator, and an extensive Enrichment Program. UAB provides our NORC over $700,000 annually to supplement the NIDDK P30 grant. The NORC Cores in Metabolism/Body Composition, Genomics, Animal Models, and Biostatistics have flourished, resulting in cost-effective research and enhanced access to cutting-edge technology that is heavily utilized by our members. Our primary theme is Obesity: Causes, Consequences, and Alleviation. Within this broad multidisciplinary theme, we are cultivating subdomains such as obesity among minorities and health disparities; obesity, caloric restriction, and aging;developmental and pediatric aspects; and mathematical/quantitative science approaches. Backed by exceptional institutional support and academic infrastructure, we request renewed funding to continue our contributions to this important area of research.

我们要求续签资金，以继续在前两个资金周期中，UAB营养肥胖研究中心（NORC）取得了成功的成功。我们的NORC在2000年获得了NIH资金，培养了多学科，协作基本临床和转化营养和肥胖研究。自从首次资助以来，NORC的研究基础已大大增长。成立于2000年，我们有60名成员；该数字在2006年上次续签时增加到了102名成员，2011年另有31％至134名成员。在2000年，我们的成员以PIS 15 R01或K-Awards的身份与营养或肥胖显然相关；这个数字在2006年增加了93％，达到29个这样的赠款，在2011年（撰写本文）中，此类数字在2011年（包括Rod Grants）中增加了17％至34（包括Rod Grants）。在过去的融资周期中，UAB的NORC直接帮助招募了至少十二个新的肥胖和营养研究人员。我们的出版物产出的绝对数量稳步增长，并且是世界上关于肥胖和营养的文献的比例。引用计数所判断的NORC出版物的影响始终超过了对肥胖和营养的同行评审文献的规范。我们的NORC领导层负责监督两项由NIH资助的T32培训补助金，用于肥胖研究，由行业赞助的肥胖培训补助金以及一系列与肥胖相关的会议。我们的NORC每年至少有四个P/F研究，一个名称的新调查员和广泛的丰富计划。 UAB每年提供超过70万美元的NORC，以补充NIDDK P30赠款。 NORC核心在代谢/人体组成，基因组学，动物模型和生物统计学中蓬勃发展，从而进行了成本效益的研究，并增强了对我们成员大量使用的尖端技术的访问。我们的主要主题是肥胖：原因，后果和缓解。在这个广泛的多学科主题中，我们正在培养少数民族和健康差异之类的子域。肥胖，热量限制和衰老；发育和小儿方面；和数学/定量科学方法。在卓越的机构支持和学术基础设施的支持下，我们要求新的资金继续我们对这一重要研究领域的贡献。