Improved treatment of congenital cytomegalovirus disease through study of placental models of pathogenesis

在澳大利亚，先天性巨细胞病毒是导致胎儿畸形的第二大常见原因，但大多数孕妇并不知道这一点，也不知道如何预防胎儿的先天性巨细胞病毒。这是一种病毒感染，可以严重损害未出生的婴儿。我们的研究目的是更多地了解病毒是如何损害婴儿的，以及抗病毒药物是否有助于减少婴儿的感染，以及减少这种感染对婴儿的损害。如果成功，这些研究将成为孕妇临床试验的基础。

Congenital CMV is the second most common cause of fetal malformation in Australia, and yet most pregnant mothers do not know about it, nor how to prevent congenital CMV in their baby. It is a viral infection that can severely damage the unborn baby. Our research aims to find more about how the virus damages the baby, and whether antiviral drugs are useful in reducing infection of the baby, and also reducing damage to the baby from such infection. If successful, these studies will be the basis for clinical trials in pregnant women.