Phase I trial of two candidate live oral salmonella enterica serovar paratyphi A

两种候选活口服肠沙门氏菌血清型甲型副伤寒杆菌的 I 期试验

• 批准号: 8332525
• 负责人: Myron Max Levine
• 金额: $ 12.28万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-03-01 至 2014-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8332525
• 关键词: ATP phosphohydrolase; Adverse reactions; Age-Years; Anabolism; Antibiotic Resistance; Antibiotics; Antibodies; Antigens; Area; Asia; Attention; Attenuated; Autologous; B-Lymphocytes; Blood specimen; Categories; Cells; Clinical; Complex; Cytotoxic T-Lymphocytes; Development; Diarrhea; Distal; Double-Blind Method; Engineering; Ensure; Enzymes; Exhibits; Feces; Fever; Flagella; Food; Frequencies; Genetic Recombination; Genotype; Homing; Immune response; Immunoglobulin A; Immunoglobulin G; Immunoglobulin-Secreting Cells; Instruction; Integrins; Life; Light; Measures; Mus; Mutation; O Antigens; Oral; Outpatients; Pathway interactions; Pattern; Peptide Hydrolases; Peripheral Blood Mononuclear Cell; Phase I Clinical Trials; Placebos; Production; Proteins; Protocols documentation; Purines; Randomized; Research; Risk; SELL gene; Safety; Salmonella; Salmonella paratyphi; Salmonella typhi; Serum; Site; Source; Syndrome; Systemic infection; T memory cell; Telephone; Typhoid Fever; Vaccination; Vaccines; Visit; bacterial H antigen; bactericide; biodefense; cell mediated immune response; cohort; cytokine; dosage; immunogenic; immunogenicity; interest; lymph nodes; mutant; oral vaccine; pathogen; prevent; purine; resistant strain; response; ward