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描述(由申请人提供):马萨诸塞州理工学院脑与认知科学系的三个核心模块需要五年的更新支持。我们是一个不断发展的部门,有十名NEI支持的研究人员进行视觉,视觉系统和眼科系统的研究。由于麦戈文家族和皮考尔基金会的大力支持,麻省理工学院成立了两个主要的新中心(麦戈文大脑研究所和皮考尔学习与记忆中心),在未来五年内将有许多新的任命,其中一些是视觉和视力控制。其中一些任命已经作出。目前,我们有19个国家眼科研究所的赠款。由十名调查人员进行的研究表明, 核心研究组包括以下研究领域:(1)视觉和听觉的神经生理学研究, 眼神经系统,(2)视觉和眼神经系统的解剖学研究,(3)视觉和视觉功能的发育研究,(4)非人灵长类动物视觉功能的心理物理学研究,(5)正常人和患者群体视觉功能的心理物理学研究,(6)视觉和眼球运动的计算分析,及(7)影像研究,以阐明不同视觉区域在影像处理中所扮演的角色。核心小组广泛使用本核心资助计划资助的两个单元,即仪器店及电子店。在过去的四年里,这些研究人员一直非常富有成效,并发表了广泛的记录在本申请。核心模块对该小组的整体研究工作做出了重大贡献,并促进了参与视觉和视觉研究的研究人员之间的互动。继续支持这两个核心设施将对我们未来的调查大有好处。此外,我们正在请求支持一个新的模块,以支持正在进行的和计划中的成像研究,由麻省理工学院的眼科研究人员进行。如果获得资助,该模块将为BCS部门的NEI支持的研究人员提供功能性脑成像的中央支持设施。
英文摘要
DESCRIPTION (provided by applicant): Five years of renewed support are requested for three Core modules in the Department of Brain and cognitive Sciences at the Massachusetts Institute of Technology. Ours is a growing department which at are sent has ten NEI-supported investigators who carry out research on vision, the visual system and the oculomotor system. Due to major support from the McGovern family and the Picower Foundation, two major new centers have been formed at MIT (the McGovern Institute for Brain Research and the Picower Center for Learning and Memory) in which numerous new appointments will be made the next five years, with several of them in vision and oculomotor control. Some of these appointments have already been made. Presently we have 19 grants from the National Eye Institute. The research carried out by the ten investigators of the Core Group includes the following areas of research: (1) neurophysiological studies of the visual and oculomotor systems, (2) anatomical studies of the visual and oculomotor systems, (3) developmental studies of the vision and visuomotor function, (4) psychophysical studies of visual functions in non-human primates, (5) psychophysical studies of visual functions in normal human and patient populations, (6) computational analyses of vision and eye movement, and (7) imaging studies to elucidate the roles various visual areas play in image processing Two of the modules supported by this Core Grant, the Instrument Shop and the Electronics Shop, are in extensive use by the Core Group. During the past four years these investigators have been very productive and have published extensively as documented in this application. The Core Modules have made significant contributions to the overall research efforts of this group and have fostered interaction among investigators involved in vision and visuomotor research. Continued support of these two Core Facilities will be of great benefit to our future investigations. Additionally, we are requesting support for a new module to support ongoing and planned imaging studies conducted by eye researchers at MIT. If funded, this module will provide a central support facility for functional brain imaging by NEI-supported investigators in the BCS department.
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Computationally Enabled Integrative Neuroscience
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Time delimited neural silencing to dissect the basis of visual object perception
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