Core Grant in Vision Research

描述（由申请人提供）：横跨文理学院、皮博迪教育学院、工程学院和医学院的范德比尔特视觉研究中心（VVRC）要求继续支持五个模块。(1)动物护理模块提供非人灵长类动物和其他大型动物的专业富集、手术支持和兽医护理以及鼠视网膜电图表型分析。(2)计算机模块提供硬件安装和维护、软件开发以进行视觉显示和实时数据采集和分析、网页维护以及为期刊、海报和网页制作插图。(3)图像处理模块有助于采集和分析功能性脑成像、光学成像、共聚焦和标准显微镜以及其他成像数据。(4)基因和蛋白质分析模块提供及时和经济的基因微阵列，蛋白质质谱和组织病理学服务。(5)Shop Module维修、设计和制造专业的光学、机械和电子仪器。行政支助也包括在内，以确保核查人员和难民中心研究和培训任务继续顺利和稳定地运作。模块由国家环境研究所资助的调查员指导，拥有有才能和经验丰富的工作人员，并提供否则无法提供的服务，或者是昂贵或缓慢的服务。在上一个赠款期间，每个模块都被三名以上的调查人员适度或广泛使用。VVRC的研究人员发表了数百篇出版物，为基础和临床视觉科学做出了重要贡献。这项核心拨款增加了范德比尔特校园内基础和临床视觉研究人员之间的合作，并与其他机构合作。核心补助金提高了我们招募世界级视觉研究人员的能力，从而在范德比尔特进行了广泛的NEI赞助的研究。VVRC研究人员的高水平表现取决于新的核心赠款支持，与范德比尔特的生物医学研究和培训的校园范围内的举措协同作用。

DESCRIPTION (provided by applicant): The Vanderbilt Vision Research Center (VVRC) spanning the College of Arts & Science, Peabody College of Education, School of Engineering and School of Medicine requests continued support for five modules. (1) The Animal Care Module provides specialized enrichment, surgical support and veterinary care of nonhuman primates and other large animals and murine electroretinogram phenotyping. (2) The Computer Module provides hardware installation and maintenance, software development for visual displays and real-time data acquisition and analysis, webpage maintenance and production of illustrations for journals, posters and web pages. (3) The Image Processing Module aids acquisition and analysis of functional brain imaging, optical imaging, confocal and standard microscopy and other imaging data. (4) The Gene & Protein Analysis Module provides timely and economical access to gene microarray, protein mass spectrometry and histopathology services. (5) The Shop Module repairs, designs and fabricates specialized optical, mechanical and electronic instruments. Administrative support is included to ensure continued smooth and stable operation of the VVRC research and training missions. Modules are directed by investigators with NEI funding, have talented and experienced staff and provide services that are otherwise not available or would be prohibitively expensive or slow. During the last grant period, each module was used moderately or extensively by more than three investigators. VVRC investigators produced several hundred publications that made fundamental contributions to basic and clinical visual science. This Core grant has increased collaborations between basic and clinical vision researchers across the Vanderbilt campus and with other institutions. The Core grant has improved our ability to recruit world-class vision researchers resulting in extensive NEI-sponsored research at Vanderbilt. The high level of performance of VVRC investigators, which depends on renewed Core grant support, synergizes with campus-wide initiatives in biomedical research and training at Vanderbilt.