HP/MICROSCOPY

组织病理学和显微科学(HPMS)服务为癌症中心成员提供 组织学、尸检、电子显微镜(扫描和电子)、光学方面的技术和专长 显微镜和细胞遗传学。与分子生物物理研究所合作，HPMS提供 癌症中心教职员工无与伦比地使用尖端显微镜系统和支持 分析和描述正常组织形态和突变体所需的基础设施 疾病病理学。通过HPMS癌症中心，成员访问小鼠尸检、组织 收集，常规和专门的组织处理和组织学染色，免疫荧光 标记，原位杂交，共聚焦显微镜，多光子显微镜，活细胞成像， 荧光显微镜和标准光学显微镜、激光捕获显微解剖(LCM)、计算机图像 染色体分析、染色体核型分析和荧光原位杂交。HPMS(以前 生物成像)在过去五年中一直得到CCSG赠款的支持。HPMS项目 带头人、研究科学家理查德·史密斯博士负责监督这项按服务收费的行动。以进一步支持 癌症中心的病理分析需要，可以接触到布朗森医生，中心的咨询 病理学家和所有推荐的后续程序都是通过HPMS安排的。六名全职 组织学家，两名显微镜专家，三名尸检技术人员，一名细胞遗传学家，咨询病理学家和 高级经理为功能基因组学中占地3772英尺2的实验室设施工作人员 大楼。史密斯博士与癌症中心用户、服务人员和中心管理人员进行沟通 确保以最有效、最具成本效益和技术上最新的方式满足研究需求。

The Histopathology & Microscopy Sciences (HPMS) Service offers Cancer Center members access to technologies and expertise in Histology, Necropsy, Electron Microscopy (scanning and electron), Light Microscopy and Cytogenetics. In combination with the Institute for Molecular Biophysics, HPMS delivers Cancer Center faculty unparalleled access to leading edge microscopy systems and the supporting infrastructure needed for the analysis and characterization of normal tissue morphology and mutant disease pathologies. Through HPMS Cancer Center, members access mouse necropsy, tissue collection, routine and specialized tissue processing and histological stains, immunofluorescence labeling, in situ hybridization, confocal microscopy, multiphoton microscopy, live-cell imaging, fluorescence and standard light microscopy, laser capture microdissection (LCM), computerized image analysis, and karyotyping and fluorescent in situ hybridization for chromosome analysis. HPMS (formerly Biological Imaging) has been supported by the CCSG grant for the past five years. The HPMS Project Leader, Research Scientist Dr. Richard Smith, oversees this fee-for-service operation. To further support the pathology analysis needs of the Cancer Center, access to Dr. Bronson, the Center's consulting Pathologist, and to all recommended follow-up procedures, are scheduled through HPMS. Six full-time histologists, two microscopists, three necropsy technicians, a cytogeneticist, consulting pathologist and senior manager staff the facility which occupies 3,772 ft2 of laboratory space in the Functional Genomics Building. Dr. Smith communicates with the Cancer Center users, Service staff and Center Administration to ensure that research needs are met in the most efficient, cost-effective and technically current manner.