Lifestyle Interventions in Overweight and Obese Pregnant Women

一项随机对照试验拟研究的效果，在一个队列的种族和民族多样化 一组超重和肥胖的孕妇，一个强化生活方式干预（ILI）相比， 孕期护理（UC）对妊娠期体重增加（GWG）、婴儿肥胖和母亲产后体重的影响 潴留ILI组的妇女将在怀孕期间接受强化咨询和团体咨询 分娩后有关行为、营养和体力活动的变化。对辅导员的访问将发生 将每周进行电话和因特网联系，并增加这种联系。母亲的年龄将在14岁和36岁时进行评估 在怀孕12周和分娩后52周。测量结果将是 人体测量、全身MRI、EchoMRI和全身体积描记术（BodPod）。幼儿 测量将包括人体测量、全身MRI、EchoMRI和全身体积描记术 （PeaPod）肥胖12周和52周。母亲和孩子将有心脏代谢危险因素 在血浆中测量。将收集有关母亲饮食摄入量和身体活动的数据 （问卷调查和加速度计），以协助咨询。收集的其他数据包括问卷 生活质量和社会经济地位。提供ILI的开支将被仔细记录，以便 可以计算干预的成本分析。这项研究的主要结果是肥胖， 婴儿出生时。我们需要180名参与者才能获得适当的权力。我们将招收210名学生， 为沿着的一些辍学者提供帮助。每位母亲在怀孕期间和产后一年内都将接受随访 交付.每个婴儿出生后将被跟踪一年。我们有能力继续跟踪这些 参与者，如果进一步的资金即将到来，因为他们都是当地的我们医院的集水区和我们的 自己的医生。如果目标实现，即儿童和母亲都从干预中受益， 在如何对待孕妇方面应该有一个范式的转变。目前有一 缺乏向这些妇女提供的与GWG和体力活动有关的行为咨询和干预。 本研究的阳性结果将为ILI的预防性干预提供依据。

A randomized controlled trial is proposed to study the effect, in a cohort of racially and ethnically diverse group of ovenweight and obese pregnant women, of an Intensive Lifestyle Intervention (ILI) compared to Usual Care (UC) on gestational weight gain (GWG), infant fatness, and mothers' post-delivery weight retention. Women in the ILI arm will receive intensive counseling during pregnancy and group counseling after delivery regarding behavior, nutrition, and physical activity change. Visits to counselors will occur weekly and additional telephone and internet contacts will occur. The mothers' will be assessed at 14 and 36 weeks of pregnancy and at 12 weeks and 52 weeks post-delivery. The measurements will be anthropometry, whole body MRI, EchoMRI, and whole body plethysmography (BodPod). The infants' measurements will be anthropometry, whole body MRI, EchoMRI, and whole body plethysmography (PeaPod) for fatness 12 weeks and 52 weeks. Mothers and children will have cardio-metabolic risk factors measured in plasma. Data will be collected regarding mothers' dietary intake and physical activity (questionnaires and accelerometry) to assist in counseling. Other data to be collected include questionnaires on quality of life, socio-economic status. Careful record will be kept of expenses in providing the ILI, so that cost analysis of the intervention can be calculated. The study is powered on the primary outcome, fatness of the infants at birth. We require 180 participants to attain appropriate power. We will enroll 210 so as to allow for some dropouts along the way. Each mother will be followed during pregnancy and for a year post delivery. Each infant will be followed for a year after birth. We have the ability to continue to follow these participants if further funding is forthcoming, as they are all local to our hospital's catchment area and our own physicians. If aims are achieved, namely that both children and mothers profit from the intervention, there should be a paradigm shift in how oven/veight pregnant women are treated. At present, there is a dearth of behavioral advice and intervention relating to GWG and physical activity provided to these women. Positive results from our studv would provide evidence for ILI preventative intervention.