Endocrinology, Metabolism and Nutrition Training Grant

内分泌、代谢和营养培训补助金

• 批准号: 8302645
• 负责人: RONALD Sherwin SWERDLOFF
• 金额: $ 3.22万
• 依托单位: LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-08-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8302645
• 关键词: Endocrinology; Grant; Training; nutrition

DESCRIPTION (provided by applicant): This application requests continued support for an existing training grant in Endocrinology, Metabolism and Nutrition supporting 3 MDs and/or PhD postdoctoral fellows. The application includes expanded opportunities for research training due to integration of the City of Hope (COH) into the Harbor-UCLA/LA BioMed Endocrine Training Program and the addition of metabolomics and fetal-maternal endocrinology training sections. The past and present Endocrinology and Nutrition Core Programs have provided research training to 134 individuals; many of whom continue or participated in full-time teaching and/or research activities, most with peer-reviewed support. Research opportunities are in 5 major areas: 1) Diabetes, Metabolism and Nutrition; 2) Metabolomics; 3) Reproductive Endocrinology and Neuroendocrinology; 4) Thyroid, Immune responses, and cell signaling; and 5) Fetal-Maternal Endocrinology. This multidisciplinary program is enhanced by three NIH funded Centers [General Clinical Research Center (GCRC) with strong Clinical Nutrition Research component; a NICHD Contraceptive Clinical Trials Center and a NCRR COH Islet Cell Resource Center] and a WHO Center in Reproduction. Physicians and basic scientists will be selected on the basis of past performance, letters of recommendation and commitment to a future academic career. The PhD trainees spend full-time in a 3 year program. MD trainees spend full-time in research or clinical effort in areas integral to their research endeavors during the 2 years supported by the training grant or in a 3 year physician scientist academic program. All fellows will participate in the UCLA-K30 and formal program of Core Research Lectures, Responsible Conduct of Research Series, seminars, conferences, and interactive sessions with their mentors and their collaborative research groups. Graduates of this program will be able to assume roles as independent investigators or transition into mentored faculty supported programs. The research facilities are primarily housed in a 25,000 sq ft research building at LA BioMed with laboratories in Endocrinology, Perinatology, and Fetal-Maternal Medicine; GCRC Core Laboratory, Stable Isotope Facility, Reproductive Morphology and Molecular Biology Units, and Computer and Biostatistics Facilities. PUBLIC HEALTH RELEVANCE: This program is highly relevant to current and emerging public health areas of diabetes, metabolic syndrome and its relation to heart disease, adult and childhood obesity, aging and population explosion and reproductive health. Graduates from this training program will be equipped with skills to conduct research in these areas.

描述（由申请人提供）： 本申请要求继续支持内分泌学，代谢和营养学现有的培训补助金，支持3个MD和/或博士博士后研究员。该应用程序包括由于希望之城（COH）整合到港口，加州大学洛杉矶分校/洛杉矶生物医学内分泌培训计划，并增加了代谢组学和胎儿-母体内分泌学培训部分扩大研究培训的机会。过去和现在的内分泌学和营养学核心计划为134人提供了研究培训;其中许多人继续或参加全职教学和/或研究活动，大多数都得到了同行评审的支持。研究机会在5个主要领域：1）糖尿病，代谢和营养; 2）代谢组学; 3）生殖内分泌学和神经内分泌学; 4）甲状腺，免疫反应和细胞信号传导;和5）胎儿-母体内分泌学。该多学科计划由三个NIH资助的中心加强[具有强大临床营养研究组成部分的一般临床研究中心（GCRC）; NICHD避孕临床试验中心和NCRR COH胰岛细胞资源中心]和WHO生殖中心。医生和基础科学家将根据过去的表现，推荐信和对未来学术生涯的承诺进行选择。博士生在一个为期3年的项目中全职工作。医学博士学员在培训补助金支持的2年内或在3年的医生科学家学术计划中，全职从事与其研究工作不可分割的领域的研究或临床工作。所有研究员将参加UCLA-K30和核心研究讲座，研究系列，研讨会，会议的负责任行为的正式计划，并与他们的导师和他们的合作研究小组的互动会议。该计划的毕业生将能够担任独立调查员或过渡到导师支持的计划。研究设施主要位于LA BioMed的一座25，000平方英尺的研究大楼内，设有内分泌学，围产期学和胎母医学实验室; GCRC核心实验室，稳定同位素设施，生殖形态学和分子生物学单位以及计算机和生物统计学设施。 公共卫生相关性：该计划与糖尿病，代谢综合征及其与心脏病，成人和儿童肥胖，老龄化和人口爆炸以及生殖健康的关系等当前和新兴的公共卫生领域高度相关。该培训计划的毕业生将具备在这些领域进行研究的技能。