BIOINFORMATICS CORE UNR

生物信息学核心UNR

• 批准号: 8360601
• 负责人: Karen Schlauch
• 金额: $ 31.48万
• 依托单位: UNIVERSITY OF NEVADA RENO
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8360601
• 关键词: Applications Grants; Area; Bioinformatics; Biomedical Research; Collaborations; Collection; Complex; Computer software; Consult; Core Facility; Custom; Data; Development; EST Library; Educational workshop; Expressed Sequence Tags; Faculty; Funding; Grant; Housing; Human Resources; Molecular Models; National Center for Research Resources; Nevada; Principal Investigator; Proteomics; Research; Research Infrastructure; Research Personnel; Resources; Running; Services; Source; Students; System; Training; Training Support; United States National Institutes of Health; Universities; Writing; base; cluster computing; computing resources; cost; design; member; metabolomics; molecular modeling; programs; research study; sound; tool; transcriptomics; web interface

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Nevada Bioinformatics Core at the University of Nevada, Reno, provides computational resources and services to Nevada faculty and students and offers training and support in the area of bioinformatics. Bioinformatics support is extended in several areas. The Core provides researchers unlimited use of a DeCypher¿ server and system that runs very complex and large BLAST queries. Users generating large EST libraries are provided with a custom EST analysis pipeline that cleanses, clusters, and annotates sequences, provides BLAST, and NCBI submission of very large sets of sequences generated both in-house as well as externally. The development of this analysis pipeline has been led by researchers at UNR. The Core furnishes software to analyze and store microarray expression data, as well as a collection of current software for molecular modeling. The Bioinformatics Core has recently purchased two storage servers that provide university-wide storage space of 48 terabytes. The Bioinformatics Core hopes to establish both intra- and inter-core usage and collaborations via these servers, offering storage to all university core facility users and personnel. In addition, the Bioinformatics Core provides access to 58 dual-processor nodes of the university's 121-node compute cluster. Access is granted to any researcher on and off campus with bioinformatics needs. All tools listed are available to the user offsite, and are maintained by the Core. Some molecular modeling software is also available for use at the Core. Consulting is also provided on a regular basis for the design of sound experiments; custom analysis of transcriptomic, metabolomic, proteomic, and sequence data; software applications; web interfaces; and bioinformatics programming. Researchers are also supported in the grant proposal writing efforts by members of the Bioinformatics Core. Core members also offer training, workshops, and seminars on various bioinformatics applications.

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 位于里诺市的内华达州大学的内华达州生物信息学核心为内华达州的教师和学生提供计算资源和服务，并在生物信息学领域提供培训和支持。 生物信息学支持扩展到几个领域。 核心为研究人员提供了无限制的使用DeCypher服务器和系统，运行非常复杂和大型的BLAST查询。 为生成大型EST文库的用户提供定制的EST分析管道，该管道净化、聚类和注释序列，提供内部以及外部生成的非常大的序列集的BLAST和NCBI提交。该分析管道的开发由UNR的研究人员领导。 Core软件用于分析和存储微阵列表达数据，以及用于分子建模的当前软件的集合。 生物信息学核心最近购买了两台存储服务器，提供48 TB的大学范围的存储空间。生物信息学核心希望通过这些服务器建立核心内和核心间的使用和协作，为所有大学核心设施用户和人员提供存储。 此外，Bioinformatics Core还提供了对该大学121个节点计算集群中58个双处理器节点的访问。访问被授予任何研究人员和校外与生物信息学的需要。 列出的所有工具都可供用户离线使用，并由核心维护。一些分子建模软件也可在核心使用。 还定期为合理实验的设计提供咨询;转录组学，代谢组学，蛋白质组学和序列数据的定制分析;软件应用程序;网络界面;和生物信息学编程。研究人员还支持生物信息学核心成员的赠款提案写作工作。 核心成员还提供关于各种生物信息学应用的培训、讲习班和研讨会。