BIOINFORMATICS CORE UNR

生物信息学核心UNR

• 批准号: 8168218
• 负责人: Karen Schlauch
• 金额: $ 34.33万
• 依托单位: UNIVERSITY OF NEVADA RENO
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8168218
• 关键词: Applications Grants; Area; Bioinformatics; Blast Cell; Collaborations; Collection; Complex; Computer Retrieval of Information on Scientific Projects Database; Computer software; Consult; Core Facility; Custom; Data; Development; EST Library; Educational workshop; Expressed Sequence Tags; Faculty; Funding; Grant; Housing; Human Resources; Institution; Molecular Models; Nevada; Proteomics; Research; Research Personnel; Resources; Running; Services; Source; Students; System; Training; Training Support; United States National Institutes of Health; Universities; Writing; base; cluster computing; computing resources; design; member; metabolomics; molecular modeling; programs; research study; sound; tool; transcriptomics; web interface

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Nevada Bioinformatics Core at the University of Nevada, Reno, provides computational resources and services to Nevada faculty and students and offers training and support in the area of bioinformatics. Bioinformatics support is extended in several areas. The Core provides researchers unlimited use of a DeCypher¿ server and system that runs very complex and large BLAST queries. Users generating large EST libraries are provided with a custom EST analysis pipeline that cleanses, clusters, and annotates sequences, provides BLAST, and NCBI submission of very large sets of sequences generated both in-house as well as externally. The development of this analysis pipeline has been led by researchers at UNR. The Core furnishes software to analyze and store microarray expression data, as well as a collection of current software for molecular modeling. The Bioinformatics Core has recently purchased two storage servers that provide university-wide storage space of 48 terabytes. The Bioinformatics Core hopes to establish both intra- and inter-core usage and collaborations via these servers, offering storage to all university core facility users and personnel. In addition, the Bioinformatics Core provides access to 58 dual-processor nodes of the university's 121-node compute cluster. Access is granted to any researcher on and off campus with bioinformatics needs. All tools listed are available to the user offsite, and are maintained by the Core. Some molecular modeling software is also available for use at the Core. Consulting is also provided on a regular basis for the design of sound experiments; custom analysis of transcriptomic, metabolomic, proteomic, and sequence data; software applications; web interfaces; and bioinformatics programming. Researchers are also supported in the grant proposal writing efforts by members of the Bioinformatics Core. Core members also offer training, workshops, and seminars on various bioinformatics applications.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 位于里诺的内华达大学的内华达生物信息学核心为内华达州的教职员工和学生提供计算资源和服务，并提供生物信息学领域的培训和支持。生物信息学支持已扩展到几个领域。 该核心为研究人员提供了无限制地使用解密服务器和运行非常复杂和大型BLAST查询的系统。为生成大型EST文库的用户提供定制的EST分析管道，该管道可对内部和外部生成的非常大的序列集进行净化、聚类和注释，提供BLAST和NCBI提交。这一分析管道的开发是由联合国研究所的研究人员领导的。 Core提供分析和存储微阵列表达数据的软件，以及一套当前用于分子建模的软件。生物信息学核心最近购买了两台存储服务器，提供大学范围内48TB的存储空间。生物信息学核心希望通过这些服务器建立核心内和核心间的使用和协作，为所有大学核心设施用户和人员提供存储。此外，生物信息学核心还提供对该大学121节点计算集群中58个双处理器节点的访问。校园内外任何有生物信息学需求的研究人员都可以访问。 所有列出的工具都可供异地用户使用，并由Core进行维护。一些分子建模软件也可以在Core上使用。 还定期为以下方面提供咨询：健全实验的设计；转录、代谢、蛋白质组和序列数据的定制分析；软件应用；网络界面；以及生物信息学编程。研究人员也得到了由生物信息学核心成员撰写的拨款提案的支持。 核心成员还提供各种生物信息学应用方面的培训、研讨会和研讨会。