Childrens Hospital Los Angeles Child Health Research Development Award

申请者描述(由申请者提供)：本申请申请继续为洛杉矶儿童医院/南加州大学凯克医学院儿科儿童健康研究职业发展奖(CHRCDA)中心提供资金。我们计划的目标是通过为初级教师儿科医生提供2至3年的75%保障时间，用于全面和个性化的基础研究教育、指导实验室培训和职业发展支持，从而培养下一代儿科医生科学家。CHRCDA学者将从从内部培训计划和全国搜索中招募的候选人中精心挑选。集中努力继续吸引妇女和任职人数不足的少数族裔申请者将是招聘工作的优先事项。要求每年资助3名奖学金获得者。儿科主席作为首席研究员，两名联合培训主任，一名招聘官员，以及内部和外部咨询委员会将监督我们的CHRCDA。学者将在资深教师指导团队的指导下进行经批准的研究，所有这些教师指导团队都有专注于基础和翻译儿科问题的广泛研究成果，有出色的外部资助记录，包括目前的NIH拨款，并在指导研究实习生方面取得了有据可查的成功。为每一位K12学者制定一个连贯的研究生涯发展计划是我们CHRCDA的基石，每个计划将包括三个组成部分。第一个组成部分是广泛的基于实验室的研究指导经验，旨在优化K12学者和他/她的指导团队之间的基础和翻译研究互动。第二部分包括一系列互动的学术生涯研讨会、演讲和研讨会，为每位学者提供成功学术生涯所需的信息和指导。第三个培训部分是一个正式的研究教育课程，根据每个学者独特和具体的研究目标、需求和兴趣而定制。这一部分的目标是向学者们提供成功开展创新研究所需的方法学、技术和生物信息学方面的知识。该计划还为独立和协作的多学科研究创造了机会，并强调研究解释、拨款提案准备、科学出版和研究陈述方面的技能。内部和外部咨询委员会将密切监测和评价学者学者的培训和工作效率。CHRCDA的持续资助将使儿科系在我们已建立的记录的基础上再接再厉，严格培养初级教职儿科科学家，使其成为成功和独立的内科科学家。 公共卫生相关性：洛杉矶/南加州大学儿童医院儿科希望有更大的能力来指导初级教职调查人员，并为这些人提供学术职业指导和基础和应用儿科研究方面的最新培训。最终，这种增加的指导、研究培训和职业发展将促进我们的初级教师儿科医生向多产的独立科学家的转变。这一行动将促进对临床相关问题的转化研究，使基础科学成果能够更快地应用于儿科临床问题。

DESCRIPTION (provided by applicant): This application requests continued funding for a Child Health Research Career Development Award (CHRCDA) center within the Department of Pediatrics at Children's Hospital Los Angeles/Keck School of Medicine, University of Southern California. The objective of our program is to develop the next generation of pediatric physician scientists by providing junior faculty pediatricians with 2 to 3 years of guaranteed 75% protected time for comprehensive and individualized basic research education, mentored laboratory training, and career development support. CHRCDA Scholars will be carefully selected from a pool of candidates recruited from internal training programs and national searches. Focused efforts to continue to attract women and underrepresented minority applicants will be a recruitment priority. Funds to support 3 Scholars per year are requested. The Chair of Pediatrics as principal investigator, two co-training directors, a recruitment officer, and Internal and External Advisory Committees will oversee our CHRCDA. Scholars will conduct approved research under the guidance of senior faculty mentoring teams, all of whom have an extensive history of research achievements focusing on basic and translational pediatric problems, an excellent record of extramural funding including current NIH grants, and documented success in mentoring research trainees. A cohesive research career development plan for each K12 Scholar is the cornerstone of our CHRCDA and each plan will have three components. The first component is an extensive laboratory based research mentoring experience designed to optimize basic and translational research interactions between the K12 Scholar and his/her mentor team. The second component consists of a series of interactive academic career workshops, presentations and seminars to provide each Scholar with information and guidance required for a successful academic career. The third training component is a formal research education curriculum customized to the unique and specific research goals, needs and interests of each Scholar. The goal of this component is to provide Scholars with the knowledge in methodologies, technologies, and bioinformatics needed for the successful conduct of innovative research. The program also creates opportunities for independent and collaborative multidisciplinary research and emphasizes skills in research interpretation, grant proposal preparation, scientific publication, and research presentation. The training and productivity of al Scholars will be closely monitored and evaluated by the Internal and External Advisory Committees. Continued CHRCDA funding will allow the Department of Pediatrics to build upon our established track record of rigorously preparing junior faculty pediatric scientists for career as successful and independent physician scientists. PUBLIC HEALTH RELEVANCE: The Department of Pediatrics at Children's Hospital Los Angeles/University of Southern California desires a greater capacity for mentoring junior faculty investigators and for providing these individuals with academic career guidance and state of the art training in basic and applied pediatric research. Ultimately, this increased mentoring, research training, and career development will enhance the transition of our junior faculty pediatricians into productive and independent scientists. This action will foster translational research on clinically relevant questions enabling basic science findings to be more rapidly applied to pediatric clinical problems.