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Intracellular Calcium Release Channels and Cardiac Arrhythmias

Intracellular Calcium Release Channels and Cardiac Arrhythmias
细胞内钙释放通道与心律失常
批准号：
8236895
负责人：
ANDREW Robert MARKS
金额：
$31.92万
依托单位：
COLUMBIA UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
项目状态：
已结题
起止时间：
2011-04-01 至 2013-03-31
来源：
https://reporter.nih.gov/project-details/8236895
关键词：
AccountingAddressAffinityAnimalsAnti-Arrhythmia AgentsArrhythmiaBindingBinding ProteinsCalciumCalcium ChannelCalcium SignalingCanis familiarisCardiacCardiac MyocytesCell physiologyCollaborationsComplementary DNAComplexCouplingCyclic AMP-Dependent Protein KinasesDataDefectDevelopmentEngineeringEquilibriumEventEvolutionExerciseExhibitsFK506FKBP1B geneFundingGated Ion ChannelGenesGeneticGoalsHeartHeart failureHomeostasisHumanImmunosuppressive AgentsIon ChannelKnock-in MouseLaboratoriesLeadLinkMacromolecular ComplexesMilrinoneMindModelingMolecularMolecular ProbesMolecular TargetMusMutant Strains MiceMutationNamesOryctolagus cuniculusPDE4D3PDE4D3 phosphodiesterasePatientsPharmaceutical PreparationsPhosphoric Monoester HydrolasesPhosphorylationPhysiologicalPlayPredispositionProcessProteinsRecombinantsRegulationRelative (related person)RoleRolipramRyR1RyR2Ryanodine Receptor Calcium Release ChannelSERCA2aSignal TransductionSiteStressSudden DeathSurfaceTacrolimus Binding Protein 1ATacrolimus Binding ProteinsTestingTherapeuticToxic effectVariantVentricular ArrhythmiaVentricular TachycardiaWorkbasecell growth regulationcytosolic receptordesignhuman diseaseinhibitor/antagonistmanmouse modelmutantnew therapeutic targetnovelphospholambanphosphoric diester hydrolasepreventprogramsprotein functionresearch studyspinophilinsudden cardiac deathuptakevoltage

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