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Investigation of the dopamine system in frontotemporal dementia

Investigation of the dopamine system in frontotemporal dementia
额颞叶痴呆中多巴胺系统的研究
批准号：
8181355
负责人：
Edward D Huey
金额：
$24.9万
依托单位：
COLUMBIA UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-05-01 至 2012-04-30
来源：
https://reporter.nih.gov/project-details/8181355
关键词：
Adverse effectsAdverse eventAffectAllelesAmendmentAnimalsAnteriorAphasiaApplications GrantsAreaAtrophicAutopsyAwardBedsBehavioralBehavioral SymptomsBilateralBiologicalBlood TestsBrainBrain DiseasesBrain imagingCaregiversCatecholsCategoriesCerebrospinal FluidCessation of lifeChemicalsChemistryClinicalCognitionCognitiveCognitive deficitsComplete Blood CountComplexComprehensionConsultCountryCross-Over StudiesDataDementiaDiagnosisDiseaseDisease ProgressionDopamineDouble-Blind MethodDyskinetic syndromeEffectivenessEligibility DeterminationEnrollmentEnsureEnzymesEvaluationEventExclusion CriteriaExperimental DesignsFamilyFamily CaregiverFingersFrontotemporal DementiaFunctional Magnetic Resonance ImagingGeneticGenetic PolymorphismGenetic StructuresGenotypeGoalsGrantGrant ReviewHealth systemHealthcare SystemsHepatotoxicityHospitalsImageImpairmentIncidenceInternal MedicineInterventionInvestigationJudgmentLaboratoriesLanguageLanguage TestsLeadLifeLiverLiver Function TestsLobeMagnetic Resonance ImagingMemory DisordersMethodsMinorMonitorMorbidity - disease rateNamesNational Institute of Neurological Disorders and StrokeNeurobehavioral ManifestationsNeuropsychological TestsNeurotransmittersNew YorkOutcomeOutpatientsParticipantPatientsPerformancePersonsPharmaceutical PreparationsPhysiciansPlacebo ControlPlacebosPlasticsPrefrontal CortexProceduresProcessProductivityProgressive Supranuclear PalsyProtocols documentationPsychotic DisordersReadingRecommendationRecording of previous eventsReportingResearchResearch DesignResearch Ethics CommitteesResearch PersonnelResearch Project GrantsRoleSafetySemantic DementiasSerious Adverse EventServicesSeveritiesSiteSocial BehaviorSocial FunctioningSocietiesSpecific qualifier valueSpeechSymptomsSyndromeSystemTemporal LobeTestingTherapeutic InterventionTimeTransferaseTransferase GeneUltrasonographyUnited StatesUnited States National Institutes of HealthWisconsinWorkabnormal involuntary movementbasebehavior measurementblood oxygen level dependentdesigndisabilitydopamine systemfollow-upfollower of religion Jewishfrontal lobe functionimprovedinhibitor/antagonistinnovationmeetingsmembermortalitynorth shore long islandresearch studyskillssocialtolcapone

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