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Investigation of the dopamine system in frontotemporal dementia

Investigation of the dopamine system in frontotemporal dementia
额颞叶痴呆中多巴胺系统的研究
批准号：
8197820
负责人：
Edward D Huey
金额：
$23.41万
依托单位：
COLUMBIA UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-05-01 至 2014-04-30
来源：
https://reporter.nih.gov/project-details/8197820
关键词：
Adverse effectsAdverse eventAffectAllelesAmendmentAnimalsAnteriorAphasiaApplications GrantsAreaAtrophicAutopsyAwardBedsBehavioral SymptomsBilateralBiologicalBlood TestsBrainBrain DiseasesBrain imagingCaregiversCatecholsCategoriesCerebrospinal FluidCessation of lifeChemicalsChemistryClinicalCognitionCognitiveCognitive deficitsComplete Blood CountComplexComprehensionConsultCountryCross-Over StudiesDataDementiaDiagnosisDiseaseDisease ProgressionDopamineDouble-Blind MethodDyskinetic syndromeEffectivenessEligibility DeterminationEnrollmentEnsureEnzymesEvaluationEventExclusion CriteriaExperimental DesignsFamilyFamily CaregiverFingersFrontotemporal DementiaFunctional Magnetic Resonance ImagingGeneticGenetic PolymorphismGenetic StructuresGenetic screening methodGenotypeGoalsGrantGrant ReviewHealth systemHealthcare SystemsHepatotoxicityHospitalsImageImpairmentIncidenceInstitutional Review BoardsInternal MedicineInterventionInvestigationJudgmentLaboratoriesLanguageLanguage TestsLeadLifeLiverLiver Function TestsMagnetic Resonance ImagingMeasuresMemory DisordersMethodsMinorMonitorMorbidity - disease rateNamesNational Institute of Neurological Disorders and StrokeNeurobehavioral ManifestationsNeuropsychological TestsNeurotransmittersNew YorkOutcomeOutpatientsParticipantPatientsPerformancePersonsPharmaceutical PreparationsPhysiciansPlacebo ControlPlacebosPlasticsPrefrontal CortexProceduresProcessProductivityProgressive Supranuclear PalsyProtocols documentationPsychotic DisordersReadingRecommendationRecording of previous eventsReportingResearchResearch DesignResearch PersonnelResearch Project GrantsRoleSafetySemantic DementiasSerious Adverse EventServicesSeveritiesSiteSocial BehaviorSocial FunctioningSocietiesSpecific qualifier valueSpeechSymptomsSyndromeSystemTemporal LobeTestingTherapeutic InterventionTimeTransferaseTransferase GeneUltrasonographyUnited StatesUnited States National Institutes of HealthWisconsinWorkabnormal involuntary movementbaseblood oxygen level dependentdesigndisabilitydopamine systemfollow-upfollower of religion Jewishfrontal lobe functionimprovedinhibitor/antagonistinnovationmeetingsmembermortalitynorth shore long islandresearch studyskillssocialtolcapone

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期刊论文(13)
专著(0)
科研奖励(0)
会议论文
FUS and TDP43 genetic variability in FTD and CBS.
DOI： 10.1016/j.neurobiolaging.2011.08.004
发表时间： 2012-05
期刊： Neurobiology of aging
影响因子： 4.2
作者： [Huey ED, Ferrari R, Moreno JH, Jensen C, Morris CM, Potocnik F, Kalaria RN, Tierney M, Wassermann EM, Hardy J, Grafman J, Momeni P]
通讯作者： Momeni P
Novel missense mutation in charged multivesicular body protein 2B in a patient with frontotemporal dementia.
DOI： 10.1097/wad.0b013e3181df20c7
发表时间： 2010-10
期刊： Alzheimer disease and associated disorders
影响因子： 2.1
作者： [Ferrari R, Kapogiannis D, Huey ED, Grafman J, Hardy J, Momeni P]
通讯作者： Momeni P
Establishing dimensionality of sexual behaviours in patients with regional brain dysfunction.
建立区域脑功能障碍患者性行为的维度。
DOI： 10.1080/02699052.2018.1497202
发表时间： 2018
期刊： Brain injury
影响因子： 1.9
作者： [Fieo,RobertA, Silverman,Hannah, O'Shea,Deirdre, Manoochehri,Masood, Grafman,Jordan, Huey,EdwardD]
通讯作者： Huey,EdwardD
Damage to the dorsolateral prefrontal cortex is associated with repetitive compulsive behaviors in patients with penetrating brain injury.
DOI： 10.1136/bmjno-2021-000229
发表时间： 2022
期刊： BMJ NEUROLOGY OPEN
影响因子： 2.7
作者： [Fremont, Rachel, Dworkin, Jordan, Manoochehri, Masood, Krueger, Frank, Huey, Edward, Grafman, Jordan]
通讯作者： Grafman, Jordan
共 8 条
    Outreach, Recruitment and Engagement Core
    Outreach, Recruitment and Engagement Core
    Using RDoC Negative and Positive Valence Paradigms to Investigate the Mechanisms of Neuropsychiatric Symptoms (NPS) in Alzheimer's Disease and Related Dementias
    Using RDoC Negative and Positive Valence Paradigms to Investigate the Mechanisms of Neuropsychiatric Symptoms (NPS) in Alzheimer's Disease and Related Dementias
    海外基金