Paul Calabresis Award in Clinical Oncology Research

临床肿瘤学研究保罗·卡拉布雷西斯奖

• 批准号: 8327653
• 负责人: MADELEINE A. KANE
• 金额: $ 72.15万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-18 至 2013-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8327653
• 关键词: Advisory Committees; Applications Grants; Area; Award; Basic Science; Clinical; Clinical Oncology; Clinical Research; Clinical Trials; Colorado; Commit; Communication; Comprehensive Cancer Center; Discipline; Doctor of Philosophy; Educational workshop; Ensure; Evaluation; Faculty; Fostering; Goals; Grant; Human; Journals; Laboratory Finding; Laboratory Study; Literature; Medical; Medical Oncology; Mentored Clinical Scientist Development Program; Mentors; Mentorship; NCI Scholars Program; Nurses; Paper; Phase; Productivity; Research; Research Personnel; Research Training; Scientist; Series; Solid; Training; Training Programs; Translations; United States National Institutes of Health; Universities; Work; abstracting; anticancer research; base; career; career development; clinical application; design; experience; flexibility; innovation; lectures; meetings; multidisciplinary; oncology; oncology program; patient oriented; patient oriented research; programs; responsible research conduct

DESCRIPTION (provided by applicant): The goal of the University of Colorado NCI Comprehensive Cancer Center (UCCC) K12 program is to train successful patient-oriented clinical and basic research investigators who can work effectively with each other in a translational, team research setting. These researchers will be able to independently design, implement and manage all phases of clinical trials research with an emphasis on translation of laboratory findings into clinical applications, as well as facilitating laboratory studies into the basic mechanisms of poorly understood clinical phenomena. The specific objectives are to: 1) Provide a flexible career development program for oncology medical doctors and Ph.D. nurses who have completed their clinical training and who are committed to a translational clinical cancer research career in an academic setting, as well as basic scientists committed to patient-oriented research; 2) Foster interdisciplinary training, communication and interaction through multiple mentoring of program scholars; 3) Create an opportunity of ongoing mentorship to support these junior faculty scholars after their formal career development program ends to ensure their successful transition to clinical research independence. Strong clinical and scientific mentors in all oncology disciplines and basic researchers will collaborate to train the Scholars. A multidisciplinary Advisory Committee will oversee the program together with Program Leader. Madeleine A. Kane, MD, Ph.D. The overall training period will last from two to seven years and will include didactics, critical evaluation of the medical literature in the subject area, clinical experience, scientifically-based clinical research training and a basic research experience for clinicians. Didactic coursework will be provided from the K30 Award supporting the Clinical Scientist Training Program enhanced by lecture series, seminars, journal clubs, workshops, attendance at national meetings and opportunities for scholars to present research results. Responsible conduct of research will be emphasized through various training experiences. Each scholar is required to submit an NIH style grant application within the last year of training. Six MD Scholars in five oncology disciplines received training during the first five-year award to UCCC. Five remain immersed in clinical-translational human-oriented research, four as UCDHSC faculty, three of whom have been promoted. Productivity includes 70 papers, 23 as first or senior author, multiple abstract presentations, 50 clinical trials initiated as PI or co-Pi, and 13 grant awards, 6 of which were by major sponsors. This K12 program has thus been highly successful in reaching the ultimate goal of producing human-oriented oncology research investigators who successfully and independently conduct solid and innovative clinical oncology research.

描述（由申请人提供）：科罗拉多大学NCI综合癌症中心（UCCC）K12计划的目标是培养成功的以患者为导向的临床和基础研究调查人员，他们可以在翻译，团队研究环境中相互有效地工作。这些研究人员将能够独立设计，实施和管理临床试验研究的所有阶段，重点是将实验室研究结果转化为临床应用，以及促进实验室研究进入对临床现象知之甚少的基本机制。具体目标是：1）为肿瘤科医生和博士提供灵活的职业发展计划。完成临床培训并致力于在学术环境中从事转化临床癌症研究事业的护士，以及致力于以患者为导向的研究的基础科学家; 2）通过对计划学者的多次指导，促进跨学科培训，沟通和互动;第三章在这些初级教师学者的正式职业发展计划结束后，创造一个持续指导的机会来支持他们，以确保他们成功过渡到临床研究的独立性。所有肿瘤学科和基础研究人员的强大临床和科学导师将合作培训学者。一个多学科咨询委员会将与项目负责人一起监督该项目。玛德琳·A Kane，MD，Ph.D.整个培训期将持续2至7年，将包括教学法、学科领域医学文献的批判性评价、临床经验、基于科学的临床研究培训和临床医生的基本研究经验。教学课程将从K30奖提供支持临床科学家培训计划，通过讲座系列，研讨会，期刊俱乐部，研讨会，参加国家会议和学者展示研究成果的机会来加强。将通过各种培训经验强调负责任地进行研究。每个学者都必须在培训的最后一年内提交NIH风格的赠款申请。五个肿瘤学科的六名医学博士学者在UCCC的第一个五年奖期间接受了培训。五个仍然沉浸在临床翻译以人为本的研究，四个作为UCDHSC教师，其中三人已被提升。生产力包括70篇论文，23篇作为第一或资深作者，多个摘要介绍，50个临床试验作为PI或co-Pi启动，13个赠款奖项，其中6个是由主要赞助商。因此，K12计划在实现以人为本的肿瘤学研究人员的最终目标方面取得了巨大成功，这些研究人员成功地独立进行了扎实和创新的临床肿瘤学研究。