K12CA086913 Renewal - Paul Calabresi Award in Clinical Oncology Research

K12CA086913 续展 - Paul Calabresi 临床肿瘤学研究奖

• 批准号: 8701241
• 负责人: MADELEINE A. KANE
• 金额: $ 107.25万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-18 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8701241
• 关键词: Advisory Committees; Applications Grants; Award; Basic Science; Cancer Research Project; Clinical; Clinical Nurse Specialists; Clinical Oncology; Clinical Pharmacists; Clinical Research; Clinical Sciences; Clinical Trials; Colorado; Commit; Communication; Discipline; Doctor of Philosophy; Ensure; Epidemiologist; Faculty; Fostering; Foundations; Funding; Future; Individual; Laboratories; Lead; Learning; Malignant Neoplasms; Medical; Medical Oncology; Mentors; Mentorship; NCI Scholars Program; Oral Surgeon; Peer Review; Pharmacology; Program Development; Psychologist; Publications; Qualifying; Research; Research Personnel; Research Training; Schools; Scientist; Training; Training Programs; United States National Institutes of Health; Universities; anticancer research; cancer therapy; career; design; flexibility; member; multidisciplinary; oncology program; professor; programs; responsible research conduct; role model; success

DESCRIPTION (provided by applicant): The purpose of this Paul Calabresi Award in Clinical Oncology Research (PCACOR) is to prepare highly qualified cancer clinical researchers called Scholars who can independently design, manage and complete cancer clinical trials by learning to communicate and coordinate with multidisciplinary teams of clinical and basic scientists using state-of-the-art laboratory analyses to personalize cancer treatment. Specific objectives are to: 1) Provide a flexible Individual Development Program for oncology medical doctors and Ph.D. clinicians (nurses, pharmacists, clinical psychologists, epidemiologists, oral surgeons) who have completed their clinical training and basic research scientists who are committed to a translational clinical cancer research career in an academic setting; 2) Foster interdisciplinary training, communication and interaction through multiple mentoring of program scholars; 3) Create an ongoing mentorship to the completed PCACOR Scholars to ensure their successful transition to clinical research independence. Strong clinical and basic science mentors provide exceptional training and role models in all oncology clinical disciplines as well in cancer basic science. A multidisciplinary Advisory Committee oversees the PCACOR directed by Program Leaders, Madeleine A. Kane, MD, Ph.D., Professor of Medical Oncology, and Andrew Thorburn, Ph.D., Professor and Chair, Department of Pharmacology, Deputy Director, UCCC. Training period lasts from two to seven years and includes Core requirements such as Responsible Conduct of Research and coursework provided by CCTSI Clinical Science Program and the UCD Graduate School. Each Scholar completes a basic science project and also designs at least one cancer clinical trial. Scholars submit an NIH style grant application within the last yea of training. The ultimate success is demonstrated by our track record. A total of fifteen junior faculty have trained as PCACOR Scholars, nine during the current funding period (out of 42 applications). Thirteen Scholars remain faculty members at University of Colorado Denver Anschutz Medical Campus (UCD-AMC); six have been promoted, all have multiple peer-reviewed publications, both clinical and basic science. Eight have obtained peer-reviewed funding from NIH, DOD ACS and/or Komen Foundation. All have designed at least one cancer clinical trial, and several PCACOR graduates lead national cancer clinical trials, cancer research training programs and clinical cancer research programs. Our PCACOR successfully produces the translational cancer clinical researchers of the future.

描述（由申请人提供）：保罗·卡拉布雷西临床肿瘤学研究奖 (PCACOR) 的目的是培养高素质的癌症临床研究人员，称为学者，他们可以通过学习与临床和基础科学家的多学科团队沟通和协调，使用最先进的实验室分析来个性化癌症治疗，从而独立设计、管理和完成癌症临床试验。具体目标是： 1) 为肿瘤医生和博士提供灵活的个人发展计划。完成临床培训的临床医生（护士、药剂师、临床心理学家、流行病学家、口腔外科医生）和致力于学术环境中转化性临床癌症研究职业的基础研究科学家； 2）通过项目学者的多重指导，促进跨学科培训、交流和互动； 3) 为已完成的 PCACOR 学者提供持续的指导，以确保他们成功过渡到临床研究独立性。强大的临床和基础科学导师为所有肿瘤临床学科以及癌症基础科学提供卓越的培训和榜样。多学科咨询委员会负责监督 PCACOR，该委员会由项目负责人、医学肿瘤学教授 Madeleine A. Kane 医学博士和博士、药理学系教授兼主任、UCCC 副主任 Andrew Thorburn 博士指导。培训期限为二到七年，包括核心要求，例如负责任的研究行为以及 CCTSI 临床科学项目和都柏林大学研究生院提供的课程。每位学者完成一项基础科学项目，并设计至少一项癌症临床试验。学者们在培训的最后一年内提交 NIH 风格的资助申请。我们的业绩记录证明了最终的成功。共有 15 名初级教师接受过 PCACOR 学者培训，其中 9 名是在当前资助期间（共 42 名申请者）。 13 名学者仍然是科罗拉多大学丹佛安舒茨医学校区 (UCD-AMC) 的教职人员；六项已获得晋升，均拥有多项同行评审出版物，包括临床和基础科学。八个已获得 NIH、DOD ACS 和/或 Komen 基金会的同行评审资金。他们都设计了至少一项癌症临床试验，并且几名 PCACOR 毕业生领导了国家癌症临床试验、癌症研究培训项目和临床癌症研究项目。我们的 PCACOR 成功培养了未来的转化癌症临床研究人员。