Diagnostics Development Core
诊断开发核心
基本信息
- 批准号:8377038
- 负责人:
- 金额:$ 51.1万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2012
- 资助国家:美国
- 起止时间:2012-03-01 至 2014-02-28
- 项目状态:已结题
- 来源:
- 关键词:AffinityAnimal ModelAnimalsAntibodiesAttenuatedBiological AssayCategoriesConsultCore FacilityDevelopmentDiagnosticDiagnostic testsEducational workshopEmerging Communicable DiseasesFeedbackGoalsGoldHarvestIndividualLaboratoriesMicrofluidicsMonitorPeptidesReagentResearchResearch PersonnelResource SharingResourcesSamplingServicesTechnologyTestingTimeTranslatingTranslationsVirulentaptamerbiodefensecostexperienceinnovationmolecular recognitionneglectpathogenpractical applicationproduct developmenttechnology developmenttherapeutic vaccinetoolworking group
项目摘要
The WRCE Diagnostics Development Core supports and enhances the efficiency of diagnostics
development projects within the WRCE by providing common access to generally-applicable technologies,
shared reagents and animal models, BSL-3 and BSL-4 testing of diagnostics, and specialized consulting
services. Two Diagnostics Workshops will be organized by the Diagnostics Development Core. Animal
challenge samples from vaccine and therapeutic projects will be harvested by the Core for efficient testing of
diagnostic technologies. Technology development activities include the development of specialized
molecular recognition reagents (e.g., antibodies and aptamers) for neglected pathogens, and microfluidics
tools for the conversion of laboratory assays into practical diagnostic platforms. Shared reagents and animal
models are economically more efficient, conserve animals, and enhance inter- and intralaboratory
comparisons of experimental diagnostics with gold standards and with each other. Moreover, we believe that
common use of the core facilities by the RCE investigators will have the additional benefit of promoting
scientific dialog beyond the boundaries of the individual laboratories. Central access to the Core's BSL-3 and
BSL-4 testing facilities allows realistic testing of candidate diagnostics with virulent agents that would be
difficult or even impossible for the individual investigator to access at reasonable cost. Finally, specialized
advice on the translation of laboratory technologies into a genuinely useful platform diagnostic test will be
provided by an experienced consultant to all diagnostics theme investigators.
WRCE诊断开发核心支持并提高诊断效率
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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{{ truncateString('Richard Willson', 18)}}的其他基金
Smartphone-based POC Testing for HIV Using Glowstick Chemistry
基于智能手机的 HIV 使用荧光棒化学进行 POC 测试
- 批准号:
10594143 - 财政年份:2023
- 资助金额:
$ 51.1万 - 项目类别:
Viral nanoparticles as ultrasensitive reporters in lateral-flow assays
病毒纳米粒子作为横流测定中的超灵敏报告基因
- 批准号:
8892732 - 财政年份:2015
- 资助金额:
$ 51.1万 - 项目类别:
Towards the Development of a Syndrome-specific Diagnostic Tool
开发针对特定症状的诊断工具
- 批准号:
8377050 - 财政年份:2012
- 资助金额:
$ 51.1万 - 项目类别:
Towards the Development of a Syndrome-specific Diagnostic Tool
开发针对特定症状的诊断工具
- 批准号:
8233015 - 财政年份:2011
- 资助金额:
$ 51.1万 - 项目类别:
Towards the Development of a Syndrome-specific Diagnostic Tool
开发针对特定症状的诊断工具
- 批准号:
7676538 - 财政年份:2009
- 资助金额:
$ 51.1万 - 项目类别:
THERMODYNAMIC BASIS OF ANTIBODY-ANTIGEN AFFINITY
抗体-抗原亲和力的热力学基础
- 批准号:
3468120 - 财政年份:1990
- 资助金额:
$ 51.1万 - 项目类别:
THERMODYNAMIC BASIS OF ANTIBODY-ANTIGEN AFFINITY
抗体-抗原亲和力的热力学基础
- 批准号:
2182486 - 财政年份:1990
- 资助金额:
$ 51.1万 - 项目类别:
THERMODYNAMIC BASIS OF ANTIBODY/ANTIGEN AFFINITY
抗体/抗原亲和力的热力学基础
- 批准号:
3468119 - 财政年份:1990
- 资助金额:
$ 51.1万 - 项目类别:
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