2012 Fibroblast Growth Factors in Development & Disease Gordon Research Conferenc

2012 成纤维细胞生长因子的开发

• 批准号: 8313143
• 负责人: Suzanne L Mansour
• 金额: $ 1.1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-03-01 至 2013-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8313143
• 关键词: Biochemistry; Biology; Cellular biology; Collaborations; Complex; Data; Development; Differentiation and Growth; Disease; Endocrinology; Environment; Family; Feedback; Fibroblast Growth Factor; Funding; Goals; Hereditary Disease; Industry; International; Malignant Neoplasms; Medical; Mentors; Metabolic Diseases; Metabolism; Natural regeneration; Organ; Pathology; Pharmacology; Physiology; Recording of previous events; Regulation; Request for Applications; Research; Research Personnel; Research Project Grants; Scientist; Signal Pathway; Signal Transduction; Site; Switzerland; Technology; Time; Tissues; Translations; Travel; abstracting; cost; developmental genetics; graduate student; human disease; improved; insight; meetings; multidisciplinary; novel; posters; repaired; symposium; tissue repair

DESCRIPTION (provided by applicant): This application requests funds to support the 2012 (4th) Gordon Research Conference (GRC) on Fibroblast Growth Factors (FGFs) in Development & Disease at Les Diablerets Conference Center, Les Diablerets, Switzerland, May 13-18, 2012 and the associated (1st) Gordon Research Seminar (GRS) on Emerging Concepts in FGF Biology, May 12-13, 2012 at the same site. The FGFs comprise a family of growth and differentiation factors with essential functions in development, metabolism, and repair of tissues and organs. Dysregulation of FGF signaling is associated with human diseases, including several developmental/genetic diseases, metabolic disorders, and malignancies. The FGF- GRC will feature talks from invited and abstract-selected speakers as well as extended poster sessions encompassing the most recent and timely research in this highly diverse field. The conference will promote interdisciplinary interactions between academic scientists, clinicians and colleagues from industry studying all aspects of FGF biology. Topics covered in this unique conference include biochemistry of the FGF signaling complex and control of downstream signaling pathways and their impact on cell biology, physiology, endocrinology, development, pharmacology, pathology and regeneration/repair. For the first time, we will also offer a pre-conference GRS, organized by junior investigators at the postdoctoral level for investigators at the graduate student, postdoctoral and junior independent levels to present their research in a mentored environment, preparing them for full participation in the subsequent GRC. The goals of the FGF-GRC & GRS organizers are to: 1) Provide an international forum for talks and posters featuring mainly unpublished data representative of the diverse approaches taken by both junior and senior FGF biologists. 2) Encourage wide-ranging formal and informal discussions of the data, stimulating new and/or improved experimental directions for all attendees. 3) Encourage networking and new collaborations among attendees, particularly those in disparate fields of FGF biology and at different levels of advancement. 4) Provide junior investigators with an up-to-date background on all aspects of FGF biology and technology, and constructive feedback on their research projects from senior investigators. In support of these goals we propose to 1) support travel and/or registration costs for a diverse selection of 25 well-established invited speakers/discussion leaders plus the 4 GRC and GRS organizers and four junior independent investigators as speakers and 2) support travel and/or registration costs for 2 well-established invited speaker/mentors, 1 junior independent investigator and 10 trainees at the graduate student or postdoctoral levels to attend the GRS. These meetings will contribute significantly to the FGF field, through presentation of the most recent and significant advances and multidisciplinary networking of scientists at all levels, increasing opportunities for translaton of new insights into FGF biology into novel medical treatments for a broad range of diseases. PUBLIC HEALTH RELEVANCE: We request funds to partially support the 2012 Gordon Research Conference (GRC) and Gordon Research Seminar (GRS) on Fibroblast Growth Factors (FGFs) in Development & Disease. The FGFs are growth and differentiation factors with essential functions in development, metabolism and repair of tissues and organs and abnormal regulation of FGF signaling is associated with human diseases, including several developmental/genetic conditions, metabolic disorders and cancer. The FGF GRC and GRS will contribute significantly to advancing the FGF field, through presentation and discussion of the most recent and significant findings, and multidisciplinary networking of scientists at all levels, increasing opportunities for translation of new insights into FGF biology into novel medical treatments for a broad range of diseases.

描述（由申请人提供）：本申请要求资金支持2012年（第4）戈登研究会议（GRC）关于LES Diablerets会议中心的发育与疾病成纤维细胞生长因素（FGF），瑞士Diablerets，Les Diablerets，5月13日，2012年5月13日，2012年5月13日至2012年，戈尔德（GRS）的戈尔德（Eminar）（GRS）2012年5月12日。 地点。 FGF组成了一个生长和分化因子家族，具有发育，代谢以及组织和器官修复的基本功能。 FGF信号的失调与人类疾病有关，包括几种发育/遗传疾病，代谢性疾病和恶性肿瘤。 FGF-GRC将以受邀和抽象选择的演讲者的演讲以及扩展的海报会议，其中包括在这个高度多样化领域的最新和及时的研究。该会议将通过研究FGF生物学各个方面的行业来促进学术科学家，临床医生和同事之间的跨学科互动。这次独特的会议涵盖的主题包括FGF信号复合物的生物化学以及对下游信号通路的控制及其对细胞生物学，生理学，内分泌学，发育，药理学，病理学和再生/修复的影响。我们还将第一次提供会议前的GRS，由初级调查员在博士后一级组织的研究生，博士后和初级独立级别的研究人员在受训的环境中介绍他们的研究，为他们做好准备，为他们做好准备，以便全面参与后续GRC。 FGF-GRC＆GRS组织者的目标是：1）为会谈和海报提供一个国际论坛，其中主要是未出版的数据代表初级和高级FGF生物学家采取的多种方法。 2）鼓励对数据进行广泛的正式和非正式讨论，为所有与会者刺激新的和/或改进的实验指示。 3）鼓励与会者之间的网络和新的合作，尤其是那些在FGF生物学领域和进步层面的不同领域。 4）为初级调查人员提供有关FGF生物学和技术各个方面的最新背景，以及从高级研究人员那里对其研究项目的建设性反馈。为了支持这些目标，我们建议1）支持旅行和/或注册费用，以选择25种良好成熟的邀请演讲者/讨论负责人，以及4个GRC和GRS组织者以及4位初级独立调查员作为演讲者和2）支持旅行和/或注册费用和/或注册费用，并为2名受邀邀请的演讲者/导师，1名初级独立的学生和10名培训者或10名学生毕业的学生或邮递员，或者毕业于研究生。 这些会议将通过向各个级别的最新和重大的进步以及对科学家的多学科网络的介绍，将对FGF领域产生重大贡献，从而增加了将新见解转化为FGF生物学的机会，以换取广泛疾病的新医疗治疗。 公共卫生相关性：我们要求资金部分支持2012年戈登研究会议（GRC）和戈登研究研讨会（GRS）关于发展与疾病的成纤维细胞增长因素（FGFS）。 FGF是生长和分化因子，在发育，代谢和组织和器官的修复方面具有重要功能，以及FGF信号的异常调节与人类疾病有关，包括几种发育/遗传疾病，代谢性疾病和癌症。 FGF GRC和GRS将通过对最新和重要的发现以及各级科学家的多学科网络的介绍和讨论，为推进FGF领域做出重大贡献， 将新见解转化为FGF生物学转化为多种疾病的新药物治疗的机会。