Biomedical Imaging and Visualization

TELESYNERGY(R) 医疗咨询工作站系统 (MCWS) 的开发始于 20 世纪 90 年代中期，并分别于 1995 年和 1997 年首次部署在 NIH 园区的信息技术中心 (CIT) 和 NCI 放射肿瘤科 (ROB) 环境中。 MCWS 允许在分布式站点之间进行实时多媒体电话会议，该系统包括用于显示 CT、MRI 或胸片的高分辨率电子观察盒。通过 NCI/CIT 合作，TELESYNERGY(R) 系统迅速成为多个国家和国际国家癌症研究所 (NCI) 项目的主要 IT 组成部分。还开发了 TELESYNERGY(R) 环境的便携式加固版本，其中包括甚小孔径终端 (VSAT) 卫星天线系统。目前，六个完整的 TELESYNERGY(R) 系统在全球范围内运行，并由 CIT 员工提供部分支持。 2012 财年期间，BIVS 继续支持小型远程肾病学系统，该系统使 NIDDK 国家肾脏病教育计划主任 Andrew Narva 博士能够在亚利桑那州祖尼市的 Zuni PHS 医院为其以前的肾病患者进行定期门诊。 2012 财年，我们继续致力于开发信号处理算法，以支持我们与 NIH 高级研究员兼 NICHD 组织生物物理和仿生学 (STBB) 科主任 Peter J. Basser 博士的长期 MRI 扩散张量成像 (DTI) 研究合作。继续开发减少 MRI 研究中运动伪影的技术。工作包括进一步开发和评估可控 MRI 体模，该体模可以表现出一系列复杂的运动，以测试 MRI 序列对运动伪影的敏感性。 2012 财年期间，还延长了对减轻这些运动伪影的校正策略的有效性的评估。 2012 财年，自动化器官和病变体积计算系统的开发已完成，该系统是应 CC 放射学和影像科学系图像处理小组组长、医学博士、哲学博士 Ronald M. Summers 的要求启动的。与改进该项目中实施的客户端/服务器环境相关的小型编程活动仍在继续，以提高整体系统效率。虽然最终目标是完全无人值守地计算指定器官和病变体积，但我们的原型正在开发为操作员辅助系统，该系统将允许计算金标准体积值。 2012 财年，继续开发新型研究型立体医学图像显示系统，该系统正在 JAVA 语言中开发，并将与 DCB、CIT 生物医学成像研究服务部门 (BIRSS) 设计的医学图像处理分析和可视化 (MIPAV) 应用程序兼容。 这种通过手部动作控制的立体医学图像显示系统正在开发中，以支持脑成像作为最初的目标应用领域。该开发平台由包含双四核处理器和集成双图形处理系统的高性能工作站提供支持，将由具有内部触觉反馈的 3D 位置传感触觉手套控制，并具有语音识别功能。 使用约翰·霍普金斯大学开发的一组算法演示了软件立体图像生成的实现，这些算法被组织为 MIPAV 图像处理环境的插件。立体大脑图像生成期间的计算延迟将在 2013 财年期间通过纳入新收购的高速图形渲染引擎（将添加到系统中）而得到极大改善。 2010 财年期间，NHGRI 未确诊疾病项目 (UDP) 负责人 William Gahl 博士和 NHGRI 研究员 Murat Sincan 博士要求 BIVS 创建一个安全门户，UDP 可以通过该门户为外部顾问提供远程安全登录到 NIH，以帮助外部专家诊断未确诊疾病。顾问是来自其他研究所的 NIH 工作人员以及外部主题专家。 2010 年 12 月，BIVS 展示了 UDP 门户网站的 beta 版本，该网站使用 NHGRI 提供的去识别化患者数据样本，指示样本病例在 NIH 内部病例经理或外部审查员看来如何。最终，该系统将为 UDP 患者提供一个未识别身份的案例研究的在线存储库。 UDP 能够通过 NIH 联合登录服务向外部顾问授予安全、经过身份验证的访问权限。 2012 财年期间，完成了 12 TB 光盘阵列和由宾夕法尼亚州立大学开发并支持数据密集型生物医学研究的 Galaxy 基于 Web 的平台的集成。这两个新组件使 UDP Portal 能够轻松地将基因组数据合并到患者病例演示中。 2012 财年期间，BIVS 继续与 CC 重症监护医学部 (CCMD) 主任 Henry Masur 博士和 CCMD 临床医生 Naomi OGrady 开展合作项目，旨在开发以图形方式呈现重症监护环境中患者状态的新方法。该原型系统偏离了现代重症监护病房患者状态显示目标标准的电子表格显示格式，并在 iPad 平台上实施，以利用多点触控显示技术和滑动屏幕控制功能。 软件开发于今年开始。还启动了所需数据网关的设计，以便临床中心电子病历 (EMR) 系统中的患者数据最终通过建筑物无线网络以加密格式传输到 iPad，并在登录过程中使用两因素身份验证。

Development of the TELESYNERGY(R) Medical Consultation WorkStation System (MCWS) was initiated in the mid 1990s, and it was first deployed in the Center for Information Technology (CIT) and NCI Radiation Oncology Branch (ROB) environments on the NIH campus in 1995 and 1997, respectively. The MCWS allows real-time multimedia teleconferencing between distributed sites, and the systems include high-resolution electronic view boxes for the display of CT, MRI or chest films. The TELESYNERGY(R) System quickly became a major IT component of several national and international National Cancer Institute (NCI) programs, through NCI/CIT collaborations. A portable, ruggedized version of the TELESYNERGY(R) environment was also developed, which includes a Very Small Aperture Terminal (VSAT) Satellite Antenna System. Currently, six full TELESYNERGY(R) Systems are operational worldwide, and are partially supported by CIT staff. During FY12, BIVS continued to support the small Telenephrology System that provides Dr. Andrew Narva, Director, National Kidney Disease Education Program, NIDDK, with the ability to conduct regularly scheduled clinics with his previous renal patients at the Zuni PHS Hospital in Zuni, AZ. In FY12, efforts continued on the development of signal processing algorithms in support of our long-term MRI Diffusion Tensor Imaging (DTI) Research collaboration with Peter J. Basser, Ph.D., NIH Senior Investigator and Chief, Section on Tissue Biophysics and Biomimetics (STBB), NICHD. Activities continued on development of techniques for reduction of motion artifacts in MRI studies. Efforts included the further development and evaluation of a controllable MRI phantom that can exhibit a range of complex motions to test the susceptibility of MRI sequences to motion artifacts. Evaluation of the efficacy of correction strategies to mitigate these motion artifacts also was extended during FY2012. During FY12, development was completed on the implementation of an automated Organ and Lesion Volume Calculation System, which was initiated at the request of Ronald M. Summers, M.D., Ph.D., Chief, Image Processing Group, Department of Radiology and Imaging Sciences, CC. Minor programming activity still continues related to the improvement of the client/server environment implemented within this project, to improve overall system efficiency. While the eventual goal is fully unattended calculation of designated organ and lesion volumes, our prototype is being developed as an operator-assisted system that will allow the calculation of gold standard volume values. In FY12, development continued on a novel research-oriented Stereo Medical Image Display System, which is being developed in the JAVA Language, and will be compatible with the Medical Image Processing Analysis and Visualization (MIPAV) Application designed by the Biomedical Imaging Research Services Section (BIRSS), DCB, CIT. This Stereo Medical Image Display System, which is to be controlled by hand-motion, is being developed to support brain imaging as the initial target application area. Powered by a high-performance workstation containing dual quad-core processors and an integrated dual graphics processing system, this development platform will be controlled by a 3D position-sensing haptics glove with internal tactile feedback, and will have a speech recognition capability. The implementation of software stereo image generation was demonstrated, utilizing a group of algorithms developed at Johns Hopkins University, which are organized as plug-ins to the MIPAV image processing environment. Computational latency, during stereo brain image generation, will be greatly improved during FY 2013 by the incorporation of a newly acquired high-speed graphics-rendering engine that will be added to the system. During FY10, BIVS was asked by Dr. William Gahl Chief of the NHGRI Undiagnosed Diseases Program (UDP), and Dr. Murat Sincan, Research Fellow, NHGRI, to create a secure portal whereby the UDP could provide outside consultants remote secure login to NIH to help as outside experts in the diagnosis of undiagnosed diseases. Consultants are NIH staff members, from other Institutes, and also outside subject matter experts. In December 2010, BIVS demonstrated the beta version of the UDP Portal website, which indicated how a sample case might appear to an internal NIH case manager or an outside reviewer, using sample de-identified patient data that was provided by NHGRI. Ultimately, this system will provide an on-line repository of de-identified case studies for UDPs patients. The UDP is able to grant secure, authenticated access to outside consultants through the NIH Federated Login Service. During FY2012 integration was completed for a 12 Terabyte Disc Array, and for the Galaxy Web-based Platform that was developed by Penn State University and supports data-intensive biomedical research. These two new components allow the UDP Portal to easily incorporate genomic data into the patient case presentation. During FY 2012, BIVS continued with a collaborative project with Dr. Henry Masur, Chief, Critical Care Medicine Department (CCMD), CC, and Naomi OGrady, Staff Clinician, CCMD, CC, aimed at the development of novel methods for the graphical presentation of the status of patients within a critical care environment. The prototype system, departs from the electronic spreadsheet display format that is the goal standard for patient status display in the modern critical care unit, and is being implemented on the iPad platform to capitalize upon multi-touch display technology and swipe screen control capability. Software development began this year. Design of the required Data Gateway was also initiated, in order to allow patient data from the Clinical Centers Electronic Medical Record (EMR) System to eventually be channeled to the iPad, via the buildings wireless network, in an encrypted format that utilizes two-factor authentication during login.