Shared Laboratory Resource Core

共享实验室资源核心

• 批准号: 8309164
• 负责人: Jorge Arevalo
• 金额: $ 13.01万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2017-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8309164
• 关键词: Biochemistry; Bioinformatics; Biological; Biological Assay; Biometry; Brazil; Collaborations; Collection; DNA; Data; Data Set; Diffusion; Environment; Equipment; Faculty; Funding; Gene Expression; Laboratories; Letters; Life; Malaria; Molecular Biology; Monitor; Nucleic Acids; Operations Research; Parasitic Diseases; Performance; Peru; Procedures; Protein Microchips; Quality Control; Reagent; Recombinant Proteins; Research; Research Infrastructure; Research Personnel; Resources; Science; Specimen; Technology; Time; Training; Visit; Work; base; data management; professor; programs; research study; skills; university student

Core C - Shared Laboratory Resources Core C will centralize and maintain quality control for parasitological and immunological procedures required by the five Projects that comprise the Center, so that the efficient use of equipment and reagent resources is maximized. This includes coordination, performance and monitoring of all work related to parasitological, immunological, nucleic acid and recombinant protein-related procedures, immunological analyses, and bioinformatics analyses among the Projects and the Data Management Core. This Core will also be critical for research capacity building with regard to data sets such as those arising from DNA, gene expression, and protein microarray experiments done in the US (at UCSD and UC Irvine, respectively) because of lack of availability in Peru or Brazil. Analysis of these data sets will be carried out by Project leaders in collaboration with the Bioinformatics unit of Core C, under the direction of Professor Mirko Zimic. This core will centralize collection and handling procedures for biological specimens, register and collation of assay results, transfer and diffusion of acquired technology and will also provide the environment for laboratory-based training for University students, postdoctoral trainees, and visiting investigators.

核心C -共享实验室资源 核心C将集中并维护寄生虫学和免疫学程序的质量控制 为满足中心五个项目的需求，使设备和试剂资源得到最大化的有效利用。这包括项目和数据管理核心之间与寄生虫学、免疫学、核酸和重组蛋白相关程序、免疫学分析和生物信息学分析相关的所有工作的协调、执行和监测。由于秘鲁或巴西缺乏可用性，该核心对数据集的研究能力建设也至关重要，例如在美国（分别在加州大学圣地亚哥分校和加州大学欧文分校）进行的DNA、基因表达和蛋白质微阵列实验。这些数据集的分析将由项目负责人在Mirko Zimic教授的指导下与Core C的生物信息学单位合作进行。 这一核心将集中生物标本的收集和处理程序、化验结果的登记和整理、所获技术的转让和传播，还将为大学生、博士后学员和访问调查人员提供实验室培训环境。