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Novel MRI Gradient Coil Manufacturing Methods

新型 MRI 梯度线圈制造方法

基本信息

批准号：
8312984
负责人：
Irving Weinberg
金额：
$ 34.02万
依托单位：
WEINBERG MEDICAL PHYSICS, LLC
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-09-01 至 2014-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8312984
关键词：
3-Dimensional Algorithms Amplifiers Animals Businesses Capital Clinical Computer software Elongation Factor Equipment Fiber Fractals Frequencies Future Goals Grant Head Heating Human Image Ink Intellectual Property Investments Lead Licensing Magnetic Resonance Imaging Manufacturer Name Marketing Medical Medical Imaging Methods Modeling Morphologic artifacts Nanotechnology National Center for Research Resources Performance Phase Physiologic pulse Price Printing Process Property Recycling Research Resistance Site Small Business Innovation Research Grant Study Section System Techniques Technology Temperature Tensile Strength Thick Time base clinical research site commercialization computer generated cost design flexibility improved innovation instrumentation interest magnetic field manufacturing process mathematical algorithm meetings millisecond nano nanosilver novel operation pre-clinical prototype satisfaction success symposium voltage

项目摘要

DESCRIPTION (provided by applicant): We aim to improve the performance of pre-clinical and clinical MRI systems, while reducing manufacturing costs. These aims will be achieved by replacing existing wire- based gradient coil construction methods with novel proprietary 3-D additive manufacturing techniques. 3-D printing of conductive nano-inks and of insulating layers (according to computer- generated designs) is a natural way to implement mathematical algorithms developed to optimize magnetic field coil configurations. We have already performed proof-of- principle studies showing that our mesoscale coil manufacturing techniques result in reduced resistance at high frequencies, a goal previously accomplished only with time- consuming processes involving the wrapping of expensive Litz wires. By including sacrificial materials into the additive manufacturing process, we have incorporated fractal branching channels for circulating coolant materials within the coil geometry. This innovation promises to significantly improve heat transfer. In Phase I, we will adapt gradient design algorithms to the additive manufacturing process, and build and characterize a prototype gradient coil. In cooperation with a strategic partner already well-established in the MRI field, we will prepare for Phase II by offering a design for a future human head-coil based on the novel manufacturing technology. PUBLIC HEALTH RELEVANCE: We aim to improve the performance of pre-clinical and clinical MRI systems, while reducing manufacturing costs. These aims will be achieved by replacing existing wire-based gradient coil construction methods with novel proprietary 3-D additive manufacturing techniques. In Phase I, we will adapt gradient design algorithms to the additive manufacturing process, and build and characterize a prototype gradient coil. In cooperation with a strategic partner already well- established in the MRI field, we will prepare for Phase II by offering a design of a human head- coil based on the novel manufacturing technology.

描述（由申请人提供）：我们的目标是提高临床前和临床MRI系统的性能，同时降低制造成本。这些目标将通过用新型专有3D增材制造技术取代现有的基于导线的梯度线圈构造方法来实现。导电纳米油墨和绝缘层的3D打印（根据计算机生成的设计）是实现为优化磁场线圈配置而开发的数学算法的自然方式。我们已经进行了原理验证研究，表明我们的中尺度线圈制造技术可以降低高频下的电阻，这一目标以前只能通过耗时的过程来实现，其中包括缠绕昂贵的利兹线。通过将牺牲材料包括到增材制造过程中，我们已经将分形分支通道用于在线圈几何形状内循环冷却剂材料。这项创新有望显著改善传热。在第一阶段，我们将使梯度设计算法适应增材制造过程，并构建和表征原型梯度线圈。通过与MRI领域的战略合作伙伴合作，我们将为第二阶段，基于新的制造技术为未来的人体头部线圈提供设计。公共卫生相关性：我们的目标是提高临床前和临床MRI系统的性能，同时降低制造成本。这些目标将通过用新的专有3D增材制造技术取代现有的基于线的梯度线圈构造方法来实现。在第一阶段，我们将使梯度设计算法适应增材制造过程，并构建和表征原型梯度线圈。通过与在MRI领域已经建立的战略合作伙伴合作，我们将通过提供基于新制造技术的人体头部线圈设计来为第二阶段做准备。