High-quality compact portable low-field head MRI with ultra-fast gradients

具有超快梯度的高质量紧凑型便携式低场头部 MRI

• 批准号: 9328157
• 负责人: Irving Weinberg
• 金额: $ 69.74万
• 依托单位: WEINBERG MEDICAL PHYSICS, LLC
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9328157
• 关键词: Athletic; Documentation; Electrolytes; Electronics; Goals; Head; Human; Hybrids; Image; Laboratories; Letters; Magnetic Resonance Imaging; Mechanics; Mission; Nerve; Neurology; Noise; Operating Rooms; Otolaryngology; Performance; Play; Production; Publishing; Resolution; Safety; Signal Transduction; System; Technology; Testing; Trauma; base; brain surgery; cryogenics; design; improved; interest; oncology; portability; prototype; safety study; volunteer

The company has shown that with by using ultra-fast strong gradients, inexpensive low- field MRI systems can collect images that are comparable in quality (signal-to-noise ratio, resolution) to conventional (e.g., 3T) MRI. The company already has made large strides in commercializing this advantage by conducting human studies (with a prototype) and by attracting investors. The prototype was built with 20th-century technology (e.g., electrolytic capacitors and cryogenic coils) which were bulky and do not lend themselves to mass production. In the proposed effort we will improve manufacturing capability by upgrading the electronics and power storage sub-systems of our low-field MRI without compromising image quality. These new subsystem designs are based on ultra-capacitor technology (originally developed for hybrid cars) and electropermanent magnets (originally designed for drones). The low-field systems will be used in neuro-operating rooms, neuro-ICUs, battlefields, athletic fields, etc. Inquiries for the product have come from serious distributors of products in the fields of neurology, brain surgery, trauma, oncology, and otolaryngology, some of whom have already invested in the company. Documentation of this interest from a subset of interested partners and/or investors is included in the Letters of Support section of this proposal.

该公司已经证明，通过使用超快的强梯度，廉价的低- 场MRI系统可以收集在质量（信噪比， 分辨率）到常规（例如，3T）MRI。该公司已经取得了长足的进步 通过进行人体研究（使用原型）将这一优势商业化， 通过吸引投资者。 原型是用20世纪的技术建造的（例如，电解电容器和 低温线圈），其体积庞大并且不适于大规模生产。在 我们将通过升级电子产品来提高制造能力 我们的低场MRI的能量存储子系统， 质量.这些新的子系统设计基于超级电容器技术（最初 为混合汽车开发）和电永磁体（最初为 无人机）。 低场系统将用于神经手术室，神经ICU，战场， 对该产品的询盘来自认真的经销商， 神经病学、脑外科、创伤、肿瘤学和耳鼻喉科领域的产品， 其中一些人已经投资了这家公司。此兴趣的文档来自 支持函中包括一部分感兴趣的合作伙伴和/或投资者 本提案的一部分。