High-quality compact portable low-field head MRI with ultra-fast gradients

该公司已经证明，通过使用超快的强烈渐变，廉价的低 野战核磁共振系统可以采集质量相当的图像(信噪比， 分辨率)到常规(例如，3T)MRI。该公司已经取得了长足的进步 通过进行人体研究(用原型)将这一优势商业化 通过吸引投资者。 原型是用20世纪的技术建造的(例如，电解电容器和 低温线圈)，体积庞大，不适合大规模生产。在 我们将通过升级电子产品来提高制造能力 和我们的低场磁共振的能量存储子系统，而不影响图像 质量。这些新的子系统设计基于超级电容器技术(最初 为混合动力汽车开发)和电磁永磁体(最初设计用于 无人机)。 低场系统将用于神经手术室、神经重症监护室、战场、 田径场等。该产品的询价来自以下重要的分销商 神经学、脑外科、创伤、肿瘤学和耳鼻喉科等领域的产品， 其中一些人已经投资了该公司。这一兴趣的文档来自 支持函中包括感兴趣的合作伙伴和/或投资者的子集 这项提案的一节。

The company has shown that with by using ultra-fast strong gradients, inexpensive low- field MRI systems can collect images that are comparable in quality (signal-to-noise ratio, resolution) to conventional (e.g., 3T) MRI. The company already has made large strides in commercializing this advantage by conducting human studies (with a prototype) and by attracting investors. The prototype was built with 20th-century technology (e.g., electrolytic capacitors and cryogenic coils) which were bulky and do not lend themselves to mass production. In the proposed effort we will improve manufacturing capability by upgrading the electronics and power storage sub-systems of our low-field MRI without compromising image quality. These new subsystem designs are based on ultra-capacitor technology (originally developed for hybrid cars) and electropermanent magnets (originally designed for drones). The low-field systems will be used in neuro-operating rooms, neuro-ICUs, battlefields, athletic fields, etc. Inquiries for the product have come from serious distributors of products in the fields of neurology, brain surgery, trauma, oncology, and otolaryngology, some of whom have already invested in the company. Documentation of this interest from a subset of interested partners and/or investors is included in the Letters of Support section of this proposal.