University of New Mexico Health Sciences Center Animal Resource Facility Improvem

描述(由申请人提供)：本G20申请的目的是申请499,885.80美元，以支持购买新的隧道垫圈、13个通风老鼠架和相关的翻新2,197 GSF/2,197 NSF，以支持在新墨西哥大学(UNM)健康科学中心(HSC)动物资源设施(ARF)安装这些设备。该项目位于生物医学研究设施(BRF)和基础医学大楼(BMSB)内的毗连空间。BRF/BMSB动物设施是ARF的主要组成部分，但核心设施还包括两个HSC卫星成像设施的住房。该项目是在BRF和BMSB ARF分别于2002年和2008年完成的前两次翻修的基础上进行改进的。这些翻修升级了机械(带有DDC控制和环境警报的暖通空调)、地板、饰面和屋顶。虽然过去的项目使ARF现代化，但我们还有其他需求：更换故障的隧道垫圈，该垫圈支持HSC的所有笼子清洗，并继续从静态微型隔离器鼠笼过渡到通风笼子。这个项目对于我们继续实现我们正在进行的战略和计划目标至关重要，这些目标是：扩大NIH和UNM HSC之间富有成效的合作伙伴关系；加强我们对HSC签名项目(脑和行为疾病、癌症、心血管和代谢疾病、儿童健康、环境健康、传染病和免疫)的支持；扩大与ARF的新发展，使其成为我们新授予的临床和翻译科学中心(CTSC)的技术核心之一；提高动物护理合规性；以及维持HSC自1973年以来一直延续的AAALAC认证。这项建议包括翻新(连接现有的管道/电气设施和相邻的装修)，在BMSB房间G10(1608 GSF/NSF)安装/更换一个已有26年历史的隧道垫圈，并延长房间排气的排气口，并增加电源插座，以支持位于BRF G82E和G82F(589 GSF/589 NSF)的13个通风鼠架的使用，这两个房间是我们的遗传小鼠繁育障碍中的主要繁殖室。现有的隧道清洗机不能维持要求的温度，漏水，干燥机不起作用，需要大量的维护，使机组在关键时间不起作用。该项目下的新设备将通过节约能源和水以及改善室内(笼子/房间)空气质量来改善动物护理，并增强UNM的可持续发展目标--特别是由于新垫圈的效率更高，故障更少，不会有水泄漏，老鼠笼子的新鲜空气从建筑中排出，改善了空气质量，减少了更换笼子的频率，减少了清洗，减少了资源，减少了劳动力，降低了核心用户的成本。如果我们要通过我们的跨学科CTSC超越发现的步伐，并以继续促进更健康的公众为主要目标，这个项目是至关重要的。

DESCRIPTION (provided by applicant): The aim of this G20 application is to request $499,885.80 to support purchase of a new tunnel washer, 13 ventilated mouse racks and associated renovation of 2,197 gsf / 2,197 nsf to support installation of this equipment at the University of New Mexico (UNM) Health Sciences Center (HSC) Animal Resource Facility (ARF). This project is located in contiguous space within the Biomedical Research Facility (BRF) and the Basic Medical Sciences Building (BMSB). The BRF/BMSB animal facilities comprise the major component of ARF but the core also includes housing in two HSC satellite imaging facilities. This project builds upon improvements from two previous renovations completed in the BRF and BMSB ARF in 2002 and 2008, respectively. Those renovations upgraded mechanical (HVAC with DDC controls and environmental alarms), floors, finishes and roofing. Although past projects modernized the ARF, we have additional needs: To replace a failing tunnel washer which supports all cage washing for HSC and continue to transition from static microisolator mouse cages to ventilated cages. This project is critical for us to continue meeting our ongoing strategic and programmatic goals which are to: Expand a productive partnership between the NIH and UNM HSC; enhance our support to the HSC Signature Programs (Brain and Behavioral Illnesses, Cancer, Cardiovascular and Metabolic Disease, Child Health, Environmental Health, and Infectious Diseases and Immunity); expand development of new emerging synergies with ARF as one of the technology cores in our newly awarded Clinical and Translational Science Center (CTSC); improve animal care compliance; and sustain AAALAC accreditation which HSC have continued since 1973. This proposal includes renovation (connection to existing plumbing/electrical service and adjacent finishes) to install/replace a 26 year old tunnel washer in BMSB room G10 (1608 gsf/nsf) and to extend exhaust ports from room exhaust and add electrical outlets that will support use of the 13 ventilated mouse racks to be located in BRF G82E and G82F (589 gsf / 589 nsf), which are the primary breeding rooms located in our genetic mouse breeding barrier. The exiting tunnel washer does not sustain required temperatures, leaks water, has a non-functional dryer and requires extensive maintenance making the unit nonfunctional at critical times. New equipment under this project will improve animal care and enhance UNM'S sustainability goals by saving energy and water and improving indoor (cage/room) air quality - specifically due to higher efficiency of the new washer with fewer failures and no water leaks and fresh air to mouse cages is exhausted from the building which improves air quality and enables reduced cage change frequency with less washing, fewer resources, reduced labor and lower costs to core users. This project is critical if we are to excel the pace of discoveries through our interdisciplinary CTSC with a primary goal to continue to promote a healthier public.