University of New Mexico Health Sciences Center Animal Resource Facility Improvem

描述（由申请人提供）：本次G20申请的目的是要求499885.80美元用于购买新的隧道洗衣机，13个通风老鼠架和相关的2197平方英尺/ 2197平方英尺的翻新，以支持在新墨西哥大学（UNM）健康科学中心（HSC）动物资源设施（ARF）安装这些设备。该项目位于生物医学研究设施（BRF）和基础医学科学大楼（BMSB）的连续空间内。BRF/BMSB动物设施是ARF的主要组成部分，但其核心还包括两个HSC卫星成像设施的住房。该项目是在2002年和2008年分别在BRF和BMSB ARF完成的两次翻新的基础上进行改进的。这些翻新升级了机械（带有DDC控制和环境警报的暖通空调）、地板、装修和屋顶。虽然过去的项目对ARF进行了现代化改造，但我们还有额外的需求：更换支持HSC所有笼子清洗的失效隧道洗衣机，并继续从静态微隔离老鼠笼过渡到通风笼子。这个项目对我们继续实现我们正在进行的战略和计划目标至关重要，这些目标是：扩大NIH和新墨西哥大学HSC之间的富有成效的伙伴关系；加强对HSC签名项目（脑和行为疾病、癌症、心血管和代谢疾病、儿童健康、环境健康、传染病和免疫）的支持；在新成立的临床与转化科学中心（CTSC）中，扩大与ARF的新协同效应的发展，将其作为技术核心之一；提高动物护理依从性；并维持自1973年以来HSC一直保持的AAALAC认证。该建议包括翻新（连接现有的管道/电气服务和邻近的装修），在BMSB房间G10 （1608 gsf/nsf）安装/更换一台26年的隧道洗衣机，并从房间排气口延长排气口，并增加电源插座，以支持位于BRF G82E和G82F （589 gsf/ 589 nsf）的13个通风老鼠架的使用，这是位于我们遗传老鼠繁殖屏障的主要繁殖房间。出口隧道洗衣机不能维持所需的温度，漏水，有一个不可用的干燥机，需要大量的维护，使机组在关键时刻无法工作。该项目的新设备将通过节约能源和水，改善室内（笼子/房间）空气质量，改善动物护理，提高新墨西哥大学的可持续发展目标——特别是由于新洗衣机效率更高，故障更少，没有漏水，老鼠笼子的新鲜空气从建筑物中排出，从而改善了空气质量，减少了换笼子的频率，减少了洗涤，减少了资源，减少了劳动力，降低了核心用户的成本。如果我们要通过跨学科的CTSC，以继续促进公众健康为主要目标，超越发现的步伐，这个项目是至关重要的。

DESCRIPTION (provided by applicant): The aim of this G20 application is to request $499,885.80 to support purchase of a new tunnel washer, 13 ventilated mouse racks and associated renovation of 2,197 gsf / 2,197 nsf to support installation of this equipment at the University of New Mexico (UNM) Health Sciences Center (HSC) Animal Resource Facility (ARF). This project is located in contiguous space within the Biomedical Research Facility (BRF) and the Basic Medical Sciences Building (BMSB). The BRF/BMSB animal facilities comprise the major component of ARF but the core also includes housing in two HSC satellite imaging facilities. This project builds upon improvements from two previous renovations completed in the BRF and BMSB ARF in 2002 and 2008, respectively. Those renovations upgraded mechanical (HVAC with DDC controls and environmental alarms), floors, finishes and roofing. Although past projects modernized the ARF, we have additional needs: To replace a failing tunnel washer which supports all cage washing for HSC and continue to transition from static microisolator mouse cages to ventilated cages. This project is critical for us to continue meeting our ongoing strategic and programmatic goals which are to: Expand a productive partnership between the NIH and UNM HSC; enhance our support to the HSC Signature Programs (Brain and Behavioral Illnesses, Cancer, Cardiovascular and Metabolic Disease, Child Health, Environmental Health, and Infectious Diseases and Immunity); expand development of new emerging synergies with ARF as one of the technology cores in our newly awarded Clinical and Translational Science Center (CTSC); improve animal care compliance; and sustain AAALAC accreditation which HSC have continued since 1973. This proposal includes renovation (connection to existing plumbing/electrical service and adjacent finishes) to install/replace a 26 year old tunnel washer in BMSB room G10 (1608 gsf/nsf) and to extend exhaust ports from room exhaust and add electrical outlets that will support use of the 13 ventilated mouse racks to be located in BRF G82E and G82F (589 gsf / 589 nsf), which are the primary breeding rooms located in our genetic mouse breeding barrier. The exiting tunnel washer does not sustain required temperatures, leaks water, has a non-functional dryer and requires extensive maintenance making the unit nonfunctional at critical times. New equipment under this project will improve animal care and enhance UNM'S sustainability goals by saving energy and water and improving indoor (cage/room) air quality - specifically due to higher efficiency of the new washer with fewer failures and no water leaks and fresh air to mouse cages is exhausted from the building which improves air quality and enables reduced cage change frequency with less washing, fewer resources, reduced labor and lower costs to core users. This project is critical if we are to excel the pace of discoveries through our interdisciplinary CTSC with a primary goal to continue to promote a healthier public.