University of New Mexico Health Sciences Center Animal Resource Facility Improvem

新墨西哥大学健康科学中心动物资源设施改善

• 批准号: 8183595
• 负责人: Kevin C O'Hair
• 金额: $ 49.99万
• 依托单位: UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-06-01 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8183595
• 关键词: Accreditation; Air; Award; Behavioral; Biomedical Research; Brain; Breeding; Cardiovascular Diseases; Center for Translational Science Activities; Child health care; Clinical; Clinical Sciences; Communicable Diseases; Community Health Centers; Core Facility; Development; Environmental Health; Equipment; Failure; Floor; Frequencies; Genetic; Goals; Health Sciences; Housing; Image; Immunity; Maintenance; Malignant Neoplasms; Mechanics; Medical; Metabolic Diseases; Mus; New Mexico; Plumbing; Resources; Science; Services; Technology; Temperature; Time; United States National Institutes of Health; Universities; Water; animal care; animal facility; animal resource; cost; exhaust; improved; meetings; programs; research facility

DESCRIPTION (provided by applicant): The aim of this G20 application is to request $499,885.80 to support purchase of a new tunnel washer, 13 ventilated mouse racks and associated renovation of 2,197 gsf / 2,197 nsf to support installation of this equipment at the University of New Mexico (UNM) Health Sciences Center (HSC) Animal Resource Facility (ARF). This project is located in contiguous space within the Biomedical Research Facility (BRF) and the Basic Medical Sciences Building (BMSB). The BRF/BMSB animal facilities comprise the major component of ARF but the core also includes housing in two HSC satellite imaging facilities. This project builds upon improvements from two previous renovations completed in the BRF and BMSB ARF in 2002 and 2008, respectively. Those renovations upgraded mechanical (HVAC with DDC controls and environmental alarms), floors, finishes and roofing. Although past projects modernized the ARF, we have additional needs: To replace a failing tunnel washer which supports all cage washing for HSC and continue to transition from static microisolator mouse cages to ventilated cages. This project is critical for us to continue meeting our ongoing strategic and programmatic goals which are to: Expand a productive partnership between the NIH and UNM HSC; enhance our support to the HSC Signature Programs (Brain and Behavioral Illnesses, Cancer, Cardiovascular and Metabolic Disease, Child Health, Environmental Health, and Infectious Diseases and Immunity); expand development of new emerging synergies with ARF as one of the technology cores in our newly awarded Clinical and Translational Science Center (CTSC); improve animal care compliance; and sustain AAALAC accreditation which HSC have continued since 1973. This proposal includes renovation (connection to existing plumbing/electrical service and adjacent finishes) to install/replace a 26 year old tunnel washer in BMSB room G10 (1608 gsf/nsf) and to extend exhaust ports from room exhaust and add electrical outlets that will support use of the 13 ventilated mouse racks to be located in BRF G82E and G82F (589 gsf / 589 nsf), which are the primary breeding rooms located in our genetic mouse breeding barrier. The exiting tunnel washer does not sustain required temperatures, leaks water, has a non-functional dryer and requires extensive maintenance making the unit nonfunctional at critical times. New equipment under this project will improve animal care and enhance UNM'S sustainability goals by saving energy and water and improving indoor (cage/room) air quality - specifically due to higher efficiency of the new washer with fewer failures and no water leaks and fresh air to mouse cages is exhausted from the building which improves air quality and enables reduced cage change frequency with less washing, fewer resources, reduced labor and lower costs to core users. This project is critical if we are to excel the pace of discoveries through our interdisciplinary CTSC with a primary goal to continue to promote a healthier public.

描述（由申请人提供）：此 G20 申请的目的是请求 499,885.80 美元，以支持购买一台新的隧道式洗衣机、13 个通风鼠标架以及 2,197 gsf / 2,197 nsf 的相关翻新，以支持在新墨西哥大学 (UNM) 健康科学中心 (HSC) 动物资源设施 (ARF) 安装该设备。该项目位于生物医学研究设施（BRF）和基础医学科学大楼（BMSB）内的连续空间。 BRF/BMSB 动物设施是 ARF 的主要组成部分，但其核心还包括两个 HSC 卫星成像设施的住房。该项目以 BRF 和 BMSB ARF 分别于 2002 年和 2008 年完成的两次翻修工程为基础进行改进。这些翻修升级了机械（带 DDC 控制和环境警报的 HVAC）、地板、饰面和屋顶。尽管过去的项目对 ARF 进行了现代化改造，但我们还有其他需求：更换支持 HSC 所有笼子清洗的故障隧道清洗机，并继续从静态微隔离器小鼠笼子过渡到通风笼子。该项目对于我们继续实现我们持续的战略和计划目标至关重要，这些目标是： 扩大 NIH 和 UNM HSC 之间富有成效的伙伴关系；加强对 HSC 特色项目（脑部和行为疾病、癌症、心血管和代谢疾病、儿童健康、环境健康以及传染病和免疫）的支持；扩大与 ARF 的新兴协同效应的发展，将其作为我们新授予的临床和转化科学中心 (CTSC) 的技术核心之一；提高动物护理依从性；并维持 HSC 自 1973 年以来一直持续的 AAALAC 认证。该提案包括翻新（连接现有管道/电力服务和相邻饰面），以在 BMSB 房间 G10 (1608 gsf/nsf) 安装/更换一台已有 26 年历史的隧道式洗衣机，并延长房间排气口的排气口，并添加电源插座，以支持使用位于 BRF G82E 和 G82F 的 13 个通风鼠标架 （589 gsf / 589 nsf），这是位于我们的遗传小鼠育种屏障中的主要育种室。现有的隧道式洗衣机无法维持所需的温度，会漏水，烘干机无法运行，并且需要大量维护，导致设备在关键时刻无法运行。该项目下的新设备将通过节省能源和水以及改善室内（笼子/房间）空气质量来改善动物护理并增强新墨西哥大学的可持续发展目标 - 特别是由于新洗衣机的效率更高，故障更少，不会漏水，并且从建筑物排出老鼠笼的新鲜空气，这改善了空气质量，并减少了笼子的更换频率，减少了洗涤次数，减少了资源，减少了劳动力，并降低了核心用户的成本。如果我们要通过跨学科 CTSC 加快发现步伐，并以继续促进公众健康为主要目标，那么这个项目至关重要。