University of New Mexico Health Sciences Center Animal Resource Facility Improvem

描述（由申请人提供）：本G20申请的目的是申请499，885.80美元，以支持购买新的隧道式清洗机、13个通风鼠标架和2，197 gsf /2，197 nsf的相关翻新，以支持在新墨西哥州大学（UNM）健康科学中心（HSC）动物资源设施（ARF）安装该设备。该项目位于生物医学研究设施（BRF）和基础医学科学大楼（BMSB）内的相邻空间。BRF/BMSB动物设施是ARF的主要组成部分，但核心还包括在两个HSC卫星成像设施中的住房。该项目建立在分别于2002年和2008年在BRF和BMSB ARF完成的两次翻新的基础上。这些翻修升级了机械设备（带有DDC控制和环境警报的HVAC）、地板、饰面和屋顶。尽管过去的项目对ARF进行了现代化改造，但我们还有其他需求：更换支持HSC所有笼清洗的失效隧道式清洗机，并继续从静态微隔离小鼠笼过渡到通风笼。该项目对我们继续实现我们正在进行的战略和计划目标至关重要，这些目标是：扩大NIH和UNM HSC之间富有成效的伙伴关系;加强我们对HSC签名计划的支持（脑和行为疾病，癌症，心血管和代谢疾病，儿童健康，环境健康，传染病和免疫）;扩大与ARF的新兴协同效应的发展，作为我们新获得的临床和转化科学中心（CTSC）的技术核心之一;提高动物护理合规性;并维持HSC自1973年以来一直持续的AAALAC认证。该提案包括翻修（连接现有管道/电气设施和相邻饰面），安装/更换BMSB G10室使用26年的隧道式洗衣机（1608 gsf/nsf），并从房间排气口延长排气口，并增加电源插座，以支持位于BRF G82 E和G82 F的13个通风鼠标架的使用（589 gsf / 589 nsf），它们是位于我们遗传小鼠繁殖屏障中的主要繁殖室。现有的隧道式洗衣机不能维持所需的温度，漏水，有一个不起作用的干燥机，需要大量的维护，使该单位在关键时刻不起作用。该项目下的新设备将改善动物护理，并通过节约能源和水以及改善室内环境来提高UNM的可持续发展目标。（笼子/房间）空气质量-特别是由于新清洗机的效率更高，故障更少，没有漏水，小鼠笼子的新鲜空气从建筑物中排出，这改善了空气质量，并能够减少笼子更换频率，减少清洗，减少资源，为核心用户减少劳动力和降低成本。如果我们要通过我们的跨学科CTSC超越发现的步伐，这个项目是至关重要的，其主要目标是继续促进更健康的公众。

DESCRIPTION (provided by applicant): The aim of this G20 application is to request $499,885.80 to support purchase of a new tunnel washer, 13 ventilated mouse racks and associated renovation of 2,197 gsf / 2,197 nsf to support installation of this equipment at the University of New Mexico (UNM) Health Sciences Center (HSC) Animal Resource Facility (ARF). This project is located in contiguous space within the Biomedical Research Facility (BRF) and the Basic Medical Sciences Building (BMSB). The BRF/BMSB animal facilities comprise the major component of ARF but the core also includes housing in two HSC satellite imaging facilities. This project builds upon improvements from two previous renovations completed in the BRF and BMSB ARF in 2002 and 2008, respectively. Those renovations upgraded mechanical (HVAC with DDC controls and environmental alarms), floors, finishes and roofing. Although past projects modernized the ARF, we have additional needs: To replace a failing tunnel washer which supports all cage washing for HSC and continue to transition from static microisolator mouse cages to ventilated cages. This project is critical for us to continue meeting our ongoing strategic and programmatic goals which are to: Expand a productive partnership between the NIH and UNM HSC; enhance our support to the HSC Signature Programs (Brain and Behavioral Illnesses, Cancer, Cardiovascular and Metabolic Disease, Child Health, Environmental Health, and Infectious Diseases and Immunity); expand development of new emerging synergies with ARF as one of the technology cores in our newly awarded Clinical and Translational Science Center (CTSC); improve animal care compliance; and sustain AAALAC accreditation which HSC have continued since 1973. This proposal includes renovation (connection to existing plumbing/electrical service and adjacent finishes) to install/replace a 26 year old tunnel washer in BMSB room G10 (1608 gsf/nsf) and to extend exhaust ports from room exhaust and add electrical outlets that will support use of the 13 ventilated mouse racks to be located in BRF G82E and G82F (589 gsf / 589 nsf), which are the primary breeding rooms located in our genetic mouse breeding barrier. The exiting tunnel washer does not sustain required temperatures, leaks water, has a non-functional dryer and requires extensive maintenance making the unit nonfunctional at critical times. New equipment under this project will improve animal care and enhance UNM'S sustainability goals by saving energy and water and improving indoor (cage/room) air quality - specifically due to higher efficiency of the new washer with fewer failures and no water leaks and fresh air to mouse cages is exhausted from the building which improves air quality and enables reduced cage change frequency with less washing, fewer resources, reduced labor and lower costs to core users. This project is critical if we are to excel the pace of discoveries through our interdisciplinary CTSC with a primary goal to continue to promote a healthier public.