CLINICAL PATHOLOGY CORE

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 临床病理学核心由4名ASCP注册医疗技术员组成，为临床兽医和核心及附属科学家提供细菌学、血液学和临床化学分析。 临床实验室有奥林巴斯AU400化学分析仪和拜耳/西门子血液分析仪的Advia 120。实验室信息系统(LIS)为血液学和化学分析仪提供了与当前TNPRC动物记录数据库的接口。LIS还提供一个接口，用于通过电子邮件将血液学、化学和微生物学报告发送给兽医。 此外，还购买了一台新的Horiba ABX血液分析仪和一台带有单独LIS的Abaxis Piccolo血液化学分析仪，以便在无法将样本运送到中心实验室时，在BSL-3空间收集感染了精选制剂的动物的数据。 2010年，临床病理中心进行了9,811次CBC，310次网织红细胞计数，评估了1,362次血涂片，进行了7,072次化学分析小组(总共86,822次分析)，36次脑脊液细胞计数，6次尿液分析，2,754次细菌/真菌培养(5,224次患者鉴定和925次环境调查培养)。只有Retic计数、血液涂片和尿检总数比去年略有下降。 艾滋病研究项目是核心服务的主要使用者。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Clinical Pathology Core is staffed by 4 ASCP registered medical technologists and provides bacteriology, hematology, and clinical chemistry analyses for the clinical veterinarians and core and affiliate scientists. The Clinical Laboratory has an Olympus AU400 chemistry analyzer and Advia 120 by Bayer/Siemens hematology analyzer. A Laboratory Information System (LIS) provides an interface for both the hematology and chemistry analyzer with the current TNPRC animal records database. The LIS also provides an interface for emailing Hematology, Chemistry and Microbiology reports to the veterinarians. In addition, a new Horiba ABX Hematology Analyzer and an Abaxis Piccolo Blood Chemistry Analyzer with separate LIS were purchased to allow data collection from animals infected with Select Agents in BSL-3 space when samples cannot be transported to the central lab. In 2010, the Clinical Pathology Core performed 9,811 CBC's, 310 reticulocyte counts, evaluated 1,362 blood smears, performed 7,072 chemistry analyses panels (86,822 analytes total) 36 CSF cell counts, 6 urinalyses, and 2,754 bacterial/fungal cultures (5,224 total identifications for patients and 925 environmental survey cultures). Only retic counts, blood smears and urinalysis totals decreased slightly from last year. The AIDS research program is a major user of core services.