OR/WA COLLABORATIVE GENETICS RESEARCH PROGRAM

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 华盛顿州和俄勒冈州国家灵长类动物研究中心共同发起了一项由华盛顿和俄勒冈国家灵长类动物研究中心共同资助的研究项目。该计划的目的是发展和支持两个中心的基因研究调查，并促进两个中心之间的合作项目。该计划包括1)改进用于基因研究的基因分型方法，2)启动表型研究以确定潜在的动物模型并开发新的基因研究项目，3)为研究人员发起的基因研究提供技术培训和专业知识。在过去的一年里，我们在ONPRC和WaNPRC之间开展了一项合作，以探索这两个NPRC猕猴自发SIB的遗传基础。已收集受试者病史和DNA样本，目前正在进行基因分析。我们还为NPRC的研究推出了一种扩展的SNP检测方法，用于验证恒河猴的祖先。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The OR/WA Collaborative Genetics Research Program is a joint effort funded equally by the Washington and Oregon National Primate Research Centers. The purpose of this program is to develop and support genetic research investigations at both Centers and to promote collaborative projects between the two centers. The program encompasses 1) improving genotyping methods for use in genetic studies, 2) initiating phenotypic studies to identify potential animal models and to develop new genetic research projects, 3) providing technical training and expertise for investigator initiated genetic research. In the past year, we developed a collaboration between the ONPRC and the WaNPRC to explore the genetic basis of spontaneous SIB in macaques at both NPRCs. Subject history and DNA samples have been collected genotype analysis is underway. We also launched an expanded SNP assay for verifying the ancestry of rhesus macaques for the NPRC studies.