2012 Cornea, Biology & Pathobiology GRC

描述（由申请人提供）：本提案要求对将于2012年3月25日至30日在加州文图拉举行的2012年角膜生物学和病理学戈登研究会议提供部分支持。本次会议的广泛和长期目标是促进角膜健康研究的创新，将世界领先的研究人员和受训人员聚集在一起，进行跨学科的讨论和合作，以提高我们对角膜生物学和病理学的理解，以及如何利用这些知识来维持角膜健康和视力。具体目标是召集该领域关键领域的主要专家和受训人员，在一个相对孤立的地点举行为期五天的会议，与会者共计150人。该计划将分为九个会议，解决基础研究和临床应用，角膜发育，系统生物学，干细胞，屏障功能，透明度，分泌，蛋白质组学和代谢组学，感染和炎症，干眼，伤口愈合，建模和工程，再生和重建的挑战。受邀演讲者将包括视觉科学领域内外的专家，他们拥有与推进角膜研究相关的专业知识。额外的发言者插槽将可用于从摘要提交中选择的最新热点话题。下午的海报会议将允许所有与会者作出贡献。将尽一切努力鼓励研究生和博士后研究员的参与，使妇女人数均等，并包括少数民族和残疾人。创新在于将一个相对较小的科学家和对角膜有共同兴趣的受训者群体聚集在一起的概念。其他会议的规模要大得多，重点是整个眼睛和/或视力，临床护理，或与角膜研究有关的特定topis。这一应用的意义在于，本次戈登研究会议将为专注于角膜及其支持组织的科学家和学员提供一个论坛，以交流思想，与研究涉及理解角膜生物学的领域外的专家会面，发展富有成效的合作，进一步推进角膜研究领域，帮助将基础科学的发现转化为临床实践，改善视力保健在国内和国际上。本提案的目的是为会议争取部分资金，以支付研究生、受训人员和其他非NEI资助的主要研究人员的注册费和/或差旅费。 公共卫生相关性：角膜的健康对视力至关重要。戈登角膜生物学和病理学研究会议与该领域的其他会议不同，因为它是一个小型但非常全面的会议，涵盖了角膜生物学研究的各个方面，包括基础科学及其转化为维持或恢复角膜健康的策略。通过汇集顶尖科学家和 来自地球仪的受训人员以一种能够分享成果和想法并形成新的合作的形式参加了这次会议，这次会议将导致对角膜有更好的了解，这将加速旨在减少角膜失明发生率的研究。

DESCRIPTION (provided by applicant): This proposal requests partial support for the 2012 Gordon Research Conference on the Biology and Pathobiology of the Cornea to be held in Ventura, California, March 25-30, 2012. The broad and long-term goal of this conference is to foster innovation in corneal health research by bring together the world's leading researchers and trainees in this field in a small format that enables cross-disciplinary discussions and collaborations so as to improve our understanding of corneal biology and pathobiology and how such knowledge could be leveraged to maintain corneal health and therefore vision. The specific aims will be to convene leading experts covering critical areas within this field and trainees, with a total of 150 participants for a five-day conference in a relatively isolated settig. The program will be structured into nine sessions addressing challenges in basic research and clinical application, corneal development, systems biology, stem cells, barrier function, transparency, secretion, proteomics and metabolomics, infection and inflammation, dry eye, wound healing, modeling and engineering, regeneration and reconstruction. Invited speakers will include experts both inside and outside the vision science field with expertise relevant to advancing corneal research. Additional speaker slots will be available for late breaking hot topics selected from abstract submissions. Afternoon poster sessions will permit all participants to contribute. Every effort will be made to encourage participation by graduate students and postdoctoral fellows, to have parity in the numbers of women, and to include minorities and persons with disabilities. Innovation lies in the concept of bringing together a relatively small group of scientist and trainees with a common interest in the cornea. Other meetings are significantly larger, focused on the whole eye and/or vision, on clinical care, or on specific topis relating to corneal research. The significance of this application is that this Gordon Research Conference will enable a forum for scientist and trainees focused on the cornea and its supportive tissues to exchange ideas, meet experts from outside the field whose research relates to understanding corneal biology, and to develop productive collaborations to further advance the field of corneal research and help translate discoveries in basic science to clinical practice and improve vision care nationally and internationally . The aim of this proposal is to secure partial funding for the conference to cover registration fees and/or travel costs for graduate students, trainees and other participants who are not NEI-funded principal investigators. PUBLIC HEALTH RELEVANCE: The heath of the cornea is critical to vision. The Gordon Research Conference on the Biology and Pathobiology of the Cornea differs from other conferences in this field in that it is a small yet intensely comprehensive meeting covering all aspects of corneal biology research, including the basic sciences and their translation to strategies for maintaining or restoring corneal health. By bringing together leading scientists and trainees from around the globe in a format that enables results and ideas to be shared, and new collaborations to be forged, this meeting will lead to a better understanding of the cornea which should accelerate research aimed at reducing the incidence of corneal blindness.