Compact, cost-effective, and operator-friendly fundus camera for early detection

紧凑、经济高效且易于操作的眼底相机，用于早期检测

• 批准号: 8394504
• 负责人: Filipp Ignatovich
• 金额: $ 49.29万
• 依托单位: LUMETRICS, INC.
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2014-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8394504
• 关键词: Address; Age; Algorithms; Automation; Back; Blindness; Caring; Childhood; Chronic Care; Clinical; Communities; Computers; Cornea; Diagnosis; Early Diagnosis; Electronics; Ensure; Equilibrium; Exhibits; Eye; Eye diseases; Funding; Fundus; Goals; Hand; Health; Health Care Costs; Health Personnel; Hospitals; Housing; Human; Image; Image Analysis; Imagery; Internal Medicine; Laboratories; Legal patent; Marketing; Mechanics; Medical; Medical Device; Methodology; Methods; Military Personnel; Miniaturization; Nursing Homes; Ophthalmoscopes; Optic Nerve; Optics; Optometry; Outcome; Patients; Performance; Phase; Population; Prevalence; Primary Health Care; Prisons; Procedures; Process; Provider; Quality of life; Retina; Retinal; Risk; Scanning; Schedule; Services; Signal Transduction; Small Business Innovation Research Grant; Specialist; Staging; System; Technology; Testing; Training; Treatment outcome; Veterans; Visit; Visual; Visual impairment; Wireless Technology; base; brass; cost; cost effective; design; digital; disability; disease diagnosis; ergonomics; improved; innovation; instrument; manufacturing process development; meetings; miniaturize; optic nerve disorder; portability; programs; prototype; success; tool

DESCRIPTION (provided by applicant): This SBIR application will revolutionize the methodology for routine examination of the back of the eye by developing an easy-to-use, pocket-sized, inexpensive digital camera for documenting retinal and optic nerve diseases. In order to reduce rates of preventable vision loss, the early diagnosis of treatable eye diseases has become increasingly important, especially as the global population ages. Early disease diagnosis is vital to preserving retinal and optic nerve function. The widely available direct ophthalmoscope is used routinely but only with difficulty. It has a small field of view, provides a fleeting image and leaves no examination record. Although ground-breaking when it was invented in the mid-19th century, this instrument is no longer a cutting edge tool in global effort to reduce vision loss. Traditional fundus cameras are a valuable technology, but they are expensive and bulky, and are typically used by trained technicians in well funded eye care centers. As a result, a lack of a quality retinal examination puts many people at risk for vision loss. Housed in a small ergonomic design, the new camera drastically simplifies fundus imaging. Quality photographs are obtained by bringing the smooth front tip of the camera into brief contact with a patient's anesthetized cornea. Image acquisition and analysis is performed automatically upon contact, and an audible signal informs the examiner the process is complete. The images are saved internally and can be wirelessly transmitted to a nearby computer for visualization and archival storage. Once the end user realizes the value of this product, concerns regarding corneal contact will dissipate, and this new camera will replace the direct ophthalmoscope with 21st century technology. This Phase II program is aimed at developing optical, mechanical, electronic and image analysis aspects of the camera, which must conform to a number of demanding performance and miniaturization specifications. The outcome of this project will be several clinically tested commercial prototypes, which can be exhibited to potential investors and customers, such as large ophthalmic companies or end users. It will serve as the basis in Phase III for high-volume manufacturing process development, registration studies, and launch. PUBLIC HEALTH RELEVANCE: The proposed ultra-portable hand-held wireless fundus camera provides an effective and simple approach to inspecting the human retina and documenting the findings. It replaces the direct ophthalmoscope as a more reliable and advanced medical device. The images can be collected during routine visits to primary care providers or specialists and in other high volume settings thereby reducing rates of vision loss and lowering health care costs, and improving the quality of life for millions of people.

描述（由申请人提供）：此SBIR申请将通过开发一种易于使用，口袋大小，廉价的用于记录视网膜和视神经疾病的数码相机，彻底改变常规检查眼后的方法。为了降低可预防的视力丧失率，可治疗眼病的早期诊断变得越来越重要，特别是随着全球人口老龄化。早期诊断对保护视网膜和视神经功能至关重要。广泛使用的直接检眼镜是常规使用，但有困难。它有一个小的视野，提供了一个