KY IDeA Networks of Biomedical Research Excellence

肯塔基州INBRE的使命是在全州范围内为生物医学和健康相关的研究和培训以及生物信息学建立基础设施和能力。在这项申请中，路易斯维尔大学与肯塔基大学、伯里亚学院、东肯塔基大学、莫尔黑德州立大学、北肯塔基大学和西肯塔基大学合作，继续发展我们的合作网络。我们网络的目标是在生物医学和健康科学领域建立有竞争力的研究和培训项目，特别是在基因组学和神经科学领域，以及建立有竞争力的生物信息学项目。这些努力将为我们的本科生、研究生、博士后研究员和年轻的教师研究者带来更好的职业发展前景。在这份申请中，我们提出了维持和发展该项目竞争性研究部分的机制，因为这方面被视为建立我们的培训和职业发展活动的关键。这将包括对现有研究人员的教学博士后和研究助理的支持，对新研究人员的计划支持，以及对新的发展研究项目的启动。对于生物信息学，我们的目标是支持具有独立竞争和/或合作发展潜力的项目。为了加强教师、博士后和未来研究人员的职业发展，我们将建立一个由经验丰富的研究人员组成的指导团队，提供关于拨款写作技巧的研讨会，并传播与最佳实践相关的材料。我们打算继续为我们的集中微阵列设备提供部分资金，这对该机构和其他机构基于基因组学的研究项目的发展至关重要，我们将继续开发倡议，以帮助我们不断增长的蛋白质组学研究基地。我们建议建立一个新的、以社区为基础的参与性研究核心。作为第一步，该核心将为肯塔基州农村地区的医疗机构建立可通过网络访问的去身份化电子健康记录。从这项活动中获得的健康信息将用于告知我们本科和研究生课程内容的未来发展以及我们的生物医学研究目标。该基础设施还将用于使患者群体表明他们对参与相关临床研究试验的兴趣。总之，我们的战略旨在加强和建设我们的基础设施和能力，并建立一个创新的下一代网络。

The Kentucky INBRE serves a statewide mission to build infrastructure and capacity for biomedical and health-related research and training as well as for bioinformatics. In this application, the University of Louisville is partnered with the University of Kentucky, Berea College, Eastern Kentucky University, Morehead State University, Northern Kentucky University and Western Kentucky University to continue the development of our collaborative network. The goals of our network are to build competitive research and training programs in the biomedical and health sciences, particularly in the fields of genomics and neuroscience, as well as to build competitive bioinformatics programs. These efforts will lead to improved prospects for career development for our undergraduate and graduate students, postdoctoral fellows, and young faculty investigators. In this application, we propose mechanisms to sustain as well as grow the competitive research component of this program as this aspect is viewed as critical to the establishment of our training and career development activities. This will include support for teaching-postdoctoral fellows and research associates for existing investigators, program support for new research investigators, and for the initiation of new developmental research projects. For bioinformatics, we aim to support projects with the potential for development as competitive independent, and/or collaborative, proposals. To enhance the career development aspects for faculty, postdoctoral fellows and prospective researchers in our program we will develop a mentoring team of proven investigators to provide workshops on grant writing skills and disseminate materials related to best practices. We intend to continue partial funding of our centralized microarray facility which is essential to the development of genomics-based research projects at this and other institutions, and we will continue to develop initiatives in aid of our growing proteomics research base. We propose to establish a new, community-based participatory research core. As a first step, this core will establish web-accessible de-identified electronic health records for health care organizations in rural Kentucky. Health information gained from this activity will be used to inform the future development of our undergraduate and graduate curriculum content and our biomedical research goals. The infrastructure will also be used to enable the patient community to indicate their interest in participating in relevant clinical research trials. In summary, our strategy is designed to strengthen and build our infrastructure and capacity and to build an innovative next generation network.