Pilot/Feasibility Studies Program of the HCV Persistence Study Group (HPSG)

PFS的总体目标是刺激与病毒持久性机制相关的创新研究。 该方案是一个机制，通过该机制，该合作研究小组将促进发展 年轻的研究人员将重点关注与HPSG的科学使命相关的领域，并将鼓励基本的 研究人员将他们的研究扩展到慢性病毒感染，通常与 HPSG直接关注这些疾病。一个重要的平行目标是促进年轻人的成长 研究人员希望增加研究这些疾病的工作人员的数量。应当 强调PFS奖励不是为了作为研究人员“在赠款之间”的“桥梁资金”而设计的 或支持有待外部资助机构支持的项目。预计PFS接受者 将导致进一步的，正在进行的研究资金由外部同行评审机构以及结果认证 在同行评审的期刊上发表。三种一般类型的PFS申请将被考虑资助： I型来自年轻研究者的研究，目前或过去没有独立的NIH支持， 与HPSG目标相关的研究计划。此类奖项的申请人 一般持有初始教师任命;高级博士后研究员也可以申请，如果有 是他们的部门在PFS内任命教师的书面承诺 支持期 第二类：来自那些目前没有专注于慢性感染新兴的科学家 病原体本身谁将扩大他们的研究，以包括问题的直接或间接 了解慢性病毒感染的重要性 第三类：研究者的新项目明显脱离了他们的既定研究 程序. 参与HPSG机构的所有成员都有资格通过PFS计划获得资金。 他们将参加HPSG研讨会，与其他中心的研究人员互动，并展示他们的发现 除向执行委员会正式报告外，还应向HPSG成员报告，如下所述。 虽然PFS计划的目标包括上述三种类型的应用程序，但类型I 建议具有最高优先级。在HPSG期间，研究者不得获得超过一项PFS奖励 补助期。

The overall goal of the PFS is to stimulate innovative research relevant to mechanisms of viral persistence. This program is one mechanism through which this collaborative Study Group will facilitate the development of young investigators focused on areas relevant to the scientific mission of the HPSG and will encourage basic investigators to extend their studies into chronic viral infections, often in collaboration with members of the HPSG directly focused on these disorders. An important parallel goal is to foster the growth of young investigators, in the hope of increasing the number of workers studying these disorders. It should be emphasized that PFS awards are not designed to serve as "bridge funding" for investigators "between grants" or to support projects with pending support from outside funding agencies. It is anticipated that PFS recipients will lead to further, ongoing research funding by external peer-reviewed agencies as well as results warranting publication in peer-reviewed journals. Three general types of PFS applications will be considered for funding: TYPE I Those from young investigators without current or past independent NIH support establishing research programs relevant to the Aims of the HPSG. Applicants for this type of award generally hold an initial faculty appointment; senior post-doctoral fellows may also apply if there is a documented commitment by their department t a faculty appointment within the PFS support period TYPE II Those from established scientists not currently focused on chronic infection with Emerging Pathogens per se who will extend their studies to encompass issues of direct of indirect importance to understanding chronic viral infection TYPE III Those from investigators with novel projects distinctly removed from their established research program. All members of the participant HPSG institutions are eligible to receive funding through the PFS program. They are expected to attend HPSG seminars, interact with other center investigators and present their findings to the members of the HPSG in addition to formal reporting to the Executive Committee as described below. While the goals of the PFS program encompasses the three types of applications noted above, TYPE I proposals have highest priority. An investigator may not receive more than one PFS award during the HPSG grant period.