Internal Monitoring of Eye Movement in Schizophrenia

精神分裂症眼动的内部监测

• 批准号: 8339804
• 负责人: Frederick Ferris
• 金额: $ 3.28万
• 依托单位: NATIONAL EYE INSTITUTE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8339804
• 关键词: Address; Computer software; Defect; Equipment; Eye; Eye Movements; Institutional Review Boards; Laboratories; Location; Monitor; Patients; Positioning Attribute; Process; Recruitment Activity; Schizophrenia; Suggestion; Time; Update

Both normal and schizophrenic subjects are asked to follow jumping target lights as their eye movements are monitored. The target lights are shown for brief periods and then extinguished before any eye movements are made, i.e. remembered targets. In one task a sequence of lights are shown and subjects are asked to move their eyes to the locations of the remembered sequence in the dark. In this way we are able to look for evidence of a defect in spatial location updating in subjects with schizophrenia. This study was approved by the IRB in September 2010. No subjects have been recruited to date because of laboratory software and equipment problems with a video eye tracker. These problems have been addressed and we have begun recruiting subjects. No results have been obtained to date.

正常受试者和精神分裂症受试者都被要求跟随跳跃的目标灯，同时监测他们的眼球运动。目标灯显示一小段时间，然后在进行任何眼球运动之前熄灭，即记住的目标。在一项任务中，一系列的灯光被显示出来，受试者被要求在黑暗中将他们的眼睛移到记忆中的序列的位置。通过这种方式，我们能够寻找精神分裂症受试者空间位置更新缺陷的证据。 这项研究于2010年9月获得了IRB的批准。到目前为止，由于视频眼球跟踪器的实验室软件和设备问题，还没有招募受试者。这些问题已经得到解决，我们已经开始招募科目。到目前为止，还没有得到任何结果。