Internal Monitoring of Eye Movement in Schizophrenia

正常人和精神分裂症患者都被要求跟随跳跃的目标灯，同时监测他们的眼球运动。目标灯会显示很短的时间，然后在眼球运动之前熄灭，也就是记住目标。在一项任务中，展示了一系列灯光，并要求受试者在黑暗中将眼睛移到记忆序列的位置。通过这种方式，我们能够寻找精神分裂症患者空间定位更新缺陷的证据。

Both normal and schizophrenic subjects are asked to follow jumping target lights as their eye movements are monitored. The target lights are shown for brief periods and then extinguished before any eye movements are made, i.e. remembered targets. In one task a sequence of lights are shown and subjects are asked to move their eyes to the locations of the remembered sequence in the dark. In this way we are able to look for evidence of a defect in spatial location updating in subjects with schizophrenia. This study was approved by the IRB in September 2010. No subjects have been recruited to date because of laboratory software and equipment problems. These have been addressed for the most part and we hope to recruit subjects for this study this fall 2010.