课题基金 / 基金详情

Regulation of Melanocyte Development and Differentiation

Regulation of Melanocyte Development and Differentiation
黑素细胞发育和分化的调节
批准号:
8349016
负责人:
thomas j hornyak
金额:
$6.55万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:

项目摘要

项目成果

thomas j hornyak的其他基金

相似基金

相关文献

中文摘要
翻译
该项目仍然活跃,主要是完成描述人类黑色素沉着综合征Waardenburg综合征小鼠模型中黑素细胞发育和存活的工作。在这项研究中,该小鼠模型的耳表型进行了研究。这些小鼠在出生后的头几天由于耳中黑色素细胞的损失而表现出听力缺陷。这些结果有助于解释一个重要的差异之间的严重的耳色素沉着表型和相对温和的皮肤色素沉着表型中观察到的遗传性发育性色素沉着疾病Waardenburg综合征和Tietz综合征的个人。这项工作目前正在审查色素细胞和黑色素瘤研究。
英文摘要
This project remains active principally to complete work describing melanocyte development and survival in a mouse model of the human deafness-pigmentation syndrome Waardenburg syndrome. In this study, the otic phenotype of this mouse model was studied. These mice exhibit a hearing deficit due to loss of melanocytes in the ear during the first several days of post-natal life. These results help to explain an important disparity between the severe otic pigmentary phenotype and the relatively mild cutaneous pigmentary phenotypes observed in individuals with the inherited developmental pigmentary disorders Waardenburg syndrome and Tietz syndrome. This work is currently under review at Pigment Cell & Melanoma Research.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Regulation of Melanocyte Development and Differentiation
  • 批准号:
    7292188
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    --
  • 负责人:
    thomas j hornyak
  • 依托单位:
Malignant Progression in Human Melanoma
  • 批准号:
    7338697
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    --
  • 负责人:
    thomas j hornyak
  • 依托单位:
Dermatoscopy in the Evaluation of Pigmented Lesions
  • 批准号:
    8349125
  • 项目类别:
  • 资助金额:
    $6.55万
  • 财政年份:
    --
  • 负责人:
    thomas j hornyak
  • 依托单位:
Isolation, Characterization, and Behavior of Melanocyte Stem Cells
  • 批准号:
    7965565
  • 项目类别:
  • 资助金额:
    $47.13万
  • 财政年份:
    --
  • 负责人:
    thomas j hornyak
  • 依托单位:
国内基金
海外基金
水稻边界发育缺陷突变体abnormal boundary development(abd)的基因克隆与功能分析
Development of a Linear Stochastic Model for Wind Field Reconstruction from Limited Measurement Data
  • 批准号:
    --
  • 项目类别:
    --
  • 资助金额:
    40万元
  • 批准年份:
    2020
  • 负责人:
    Vikrant Gupta
  • 依托单位: