RHESUS BREEDING COLONY IN NEPAL AND IMPORTATION TO USA

尼泊尔恒河猴养殖场并进口到美国

• 批准号: 8357648
• 负责人: JOHN L VANDEBERG
• 金额: $ 9.96万
• 依托单位: TEXAS BIOMEDICAL RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357648
• 关键词: AIDS vaccine development; Acquired Immunodeficiency Syndrome; Address; Animal Experimentation; Animals; Biological; Biomedical Research; Breeding; Characteristics; Funding; Grant; Infectious Agent; Laws; Macaca mulatta; Monkeys; National Center for Research Resources; Nepal; Primates; Principal Investigator; Production; Research; Research Infrastructure; Resources; Severities; Source; United States; United States National Institutes of Health; cost; meetings; vaccine development; weapons

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. There is a severe shortage of rhesus monkeys (Macaca mulatta) required to fulfill critical needs in research on AIDS, on development of vaccines against infectious agents that could be used as biological weapons, and on a wide variety of other topics in biomedical research. Rhesus macaques derived from monkeys of Indian origin have unique characteristics that are particularly valuable in research on the development of AIDS vaccines. Despite the recent expansion of breeding colonies in the United States, the shortage of these important research animals is actually increasing in severity, accentuating the need for new sources of Indian-type rhesus. Indian-type rhesus macaques exist in large numbers throughout many regions of Nepal. The production and exportation of captive born rhesus macaques is approved under Nepalese law. The objective of this proposal is to address the urgent need for a new source of Indian-type rhesus macaques for use in biomedical research by developing a captive breeding colony in Nepal. We are developing a self-sustaining colony capable of supplying 75 animals per year to the US to meet critical biomedical research needs.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 恒河猴（Macaca mulatta）严重短缺，无法满足艾滋病研究、开发可用作生物武器的传染性疫苗以及生物医学研究中各种其他主题的关键需求。 来自印度血统的猴子的恒河猴具有独特的特征，这对于艾滋病疫苗的开发研究特别有价值。 尽管美国的繁殖群体最近有所扩大，但这些重要研究动物的短缺实际上正在日益严重，这加剧了对印度型恒河猴新来源的需求。 印度型恒河猴在尼泊尔许多地区大量存在。 尼泊尔法律批准圈养恒河猴的生产和出口。 该提案的目的是通过在尼泊尔建立圈养繁殖群来满足生物医学研究中对印度型恒河猴新来源的迫切需求。 我们正在开发一个能够自我维持的群体，每年能够向美国供应 75 只动物，以满足关键的生物医学研究需求。