NIH-Owned Chimpanzee Research Resource at the SNPRC

NIH 拥有的 SNPRC 黑猩猩研究资源

• 批准号: 8543216
• 负责人: JOHN L VANDEBERG
• 金额: $ 268.19万
• 依托单位: TEXAS BIOMEDICAL RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-05 至 2016-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8543216
• 关键词: Acquired Immunodeficiency Syndrome; Address; Aggressive behavior; Animal Behavior; Animals; Behavior Therapy; Behavioral; Biochemical; Biomedical Research; Categories; Characteristics; Clinical; Cognition; Cognitive; Communicable Diseases; Communities; Companions; Complex; Data; Databases; Disease; Evolution; Food; Future; Gene Expression Profile; Genes; Genetic; HIV; Health Status; Heart Diseases; Hepatitis; Hepatitis B Virus; Hepatitis C virus; Housing; Human; Individual; Infection; Intervention; Isoptera; Liver; Measures; Messenger RNA; MicroRNAs; Modeling; National Center for Research Resources; Occupational; Occupations; Pan Genus; Perch; Peripheral Blood Mononuclear Cell; Pharmaceutical Preparations; Physiological; Physiology; Play; Pongidae; Population; Primates; Radio; Recommendation; Recording of previous events; Relative (related person); Research; Research Subjects; Resources; Role; Sampling; Schedule; Sensory; Services; Socialization; Specialist; Structure; Television; Testing; Toy; Training; United States National Institutes of Health; Variant; biomedical resource; cohort; design; efficacy testing; environmental enrichment for laboratory animals; feeding; fruits and vegetables; humanized monoclonal antibodies; intervention program; man; meetings; novel; novel therapeutic intervention; programs; public education; safety testing; social

The overall objective of this project is to maintain an NIH-owned biomedical resource consisting of 136 chimpanzees and to manage it to serve the national biomedical community needs. The sole specific aim of this supplement over the next year is to maintain a stable, healthy, and well defined population of chimpanzees and to coordinate the relocation of chimpanzees from the New Iberia Research Center to the Southwest National Primate Center. The transfer of the 111 NIH-owned chimpanzees currently located at the New Iberia center to the Southwest center will bring the total number of NIH-owned chimpanzees at Southwest to 136. Relocation details are provided separately. In addition to routine husbandry, high quality behavioral management and enrichment are critical for meeting the social and cognitive needs of the chimpanzees. Aspects of the behavioral services program at the Southwest center include socialization and animal training, environmental enrichment, behavioral management, and staff training. Categories of environmental enrichment include social enrichment (housing with compatible social companions), structural enrichment (e.g., climbing structures, perches. Swings), manipulable enrichment (e.g., chew toys and balls), food enrichment (4x daily fruit and vegetables in addition to special food treats provided by enrichment specialists), sensory enrichment (television, mirrors, radio, novel scents), and occupation enrichement (e.g. termite feeders and food puzzles). Behavioral management is a large part of the total program. In situations where behavioral concerns arise (e.g. increased aggression in a group), observations are conducted and recommendations are made to address the issue (e.g., cooperative feeding or reorganization of the group). With individual animal behavior problems, that animal is referred to the behavioral intervention program manager who conducts an assessment and develops an intervention plan (e.g., training/stationing, occupational enrichment such as food puzzles, or changes in the caretaker routine.

该项目的总体目标是维持由136只黑猩猩组成的美国国立卫生研究院拥有的生物医学资源，并对其进行管理，以满足国家生物医学界的需求。在接下来的一年里，这项补充的唯一具体目标是维持一个稳定、健康和明确的黑猩猩种群，并协调黑猩猩从新伊比利亚研究中心迁往西南国家灵长类动物中心的工作。