EFFECTS OF SHAMPOO AND WATER WASHING ON HAIR CORTISOL CONCENTRATIONS
洗发水和水洗对头发皮质醇浓度的影响
基本信息
- 批准号:8358018
- 负责人:
- 金额:$ 5.4万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2011
- 资助国家:美国
- 起止时间:2011-05-01 至 2012-04-30
- 项目状态:已结题
- 来源:
- 关键词:Biological MarkersChronic stressElementsExposure toFundingGrantHairHair shaft structureHousingHumanHydrocortisoneIn VitroLaboratoriesMacaca mulattaMeasurementMonkeysNational Center for Research ResourcesNatureNeckNew EnglandPrimatesPrincipal InvestigatorResearchResearch InfrastructureResourcesSourceTestingUnited States National Institutes of HealthWaterbasecostnonhuman primate
项目摘要
This subproject is one of many research subprojects utilizing the resources
provided by a Center grant funded by NIH/NCRR. Primary support for the subproject
and the subproject's principal investigator may have been provided by other sources,
including other NIH sources. The Total Cost listed for the subproject likely
represents the estimated amount of Center infrastructure utilized by the subproject,
not direct funding provided by the NCRR grant to the subproject or subproject staff.
Measurement of cortisol in hair is emerging as a biomarker for chronic stress in human and nonhuman primates. Because of its external nature, hair is potentially vulnerable to a loss of cortisol from within the hair shaft due to repeated exposure to various substances such as shampoo (in humans) and water (in free-ranging monkeys). This study examined the influence of both factors on the hair cortisol levels of indoor laboratory housed rhesus monkeys. The effect of shampoo and water cannot be tested in humans because of the need to have hair that had no prior exposure to these elements. Hair was shampooed and exposed to water in vitro (i.e., after it had been gently shaved from the nape of the neck of the rhesus monkeys).
这个子项目是许多利用资源的研究子项目之一
由NIH/NCRR资助的中心拨款提供。子项目的主要支持
而子项目的主要调查员可能是由其他来源提供的,
包括其它NIH来源。 列出的子项目总成本可能
代表子项目使用的中心基础设施的估计数量,
而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。
毛发中皮质醇的测量正在成为人类和非人类灵长类动物慢性应激的生物标志物。由于其外在的性质,头发可能容易受到皮质醇从毛干内的损失,由于反复暴露于各种物质,如洗发水(人类)和水(自由放养的猴子)。 本研究探讨了这两种因素对室内实验室饲养的恒河猴毛发皮质醇水平的影响。 洗发水和水的效果不能在人类身上测试,因为需要有头发,没有事先暴露于这些元素。 将头发用洗发剂洗涤并在体外暴露于水(即,在从恒河猴的颈背轻轻地剃掉之后)。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Melinda Ann Novak其他文献
Melinda Ann Novak的其他文献
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{{ truncateString('Melinda Ann Novak', 18)}}的其他基金
THE EFFECTS OF FENTANYL, AN OPIOID AGONIST, ON SIB
芬太尼(一种阿片类药物激动剂)对 SIB 的影响
- 批准号:
8358019 - 财政年份:2011
- 资助金额:
$ 5.4万 - 项目类别:
HAIR CORTISOL PREDICTS ANXIETY AND BEHAVIOR IN INFANT MONKEYS
头发皮质醇可预测幼猴的焦虑和行为
- 批准号:
8357986 - 财政年份:2011
- 资助金额:
$ 5.4万 - 项目类别:
ESTABLISHING PREDICTORS OF SIB IN RHESUS MONKEYS
建立恒河猴 SIB 的预测因子
- 批准号:
8357931 - 财政年份:2011
- 资助金额:
$ 5.4万 - 项目类别:
EFFECTS OF THE ENVIRONMENT ON HAIR CORTISOL LEVELS IN MACAQUES AND MAMMALS
环境对猕猴和哺乳动物毛发皮质醇水平的影响
- 批准号:
8358017 - 财政年份:2011
- 资助金额:
$ 5.4万 - 项目类别:
ASSESSMENT OF COGNITIVE FUNCTION AND RELATIONSHIP TO REACTIVITY
认知功能及其与反应性关系的评估
- 批准号:
8172838 - 财政年份:2010
- 资助金额:
$ 5.4万 - 项目类别:
HAIR CORTISOL PREDICTS ANXIETY AND BEHAVIOR IN INFANT MONKEYS
头发皮质醇可预测幼猴的焦虑和行为
- 批准号:
8172908 - 财政年份:2010
- 资助金额:
$ 5.4万 - 项目类别:
ESTABLISHING PREDICTORS OF SIB IN RHESUS MONKEYS
建立恒河猴 SIB 的预测因子
- 批准号:
8172839 - 财政年份:2010
- 资助金额:
$ 5.4万 - 项目类别:
BEHAVIORAL AND HORMONAL RESPONSES OF MONKEYS TO FG7142
猴子对 FG7142 的行为和荷尔蒙反应
- 批准号:
8172863 - 财政年份:2010
- 资助金额:
$ 5.4万 - 项目类别:
BEHAVIORAL AND HORMONAL RESPONSES OF MONKEYS TO FG7142
猴子对 FG7142 的行为和荷尔蒙反应
- 批准号:
7958371 - 财政年份:2009
- 资助金额:
$ 5.4万 - 项目类别:
ESTABLISHING PREDICTORS OF SIB IN RHESUS MONKEYS
建立恒河猴 SIB 的预测因子
- 批准号:
7958343 - 财政年份:2009
- 资助金额:
$ 5.4万 - 项目类别:
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