MODELING & RADIOLYTIC FOOTPRINTING USED TO MAP OLIGOSACCHARIDE BINDING SITES

造型

• 批准号: 8361796
• 负责人: ROBERT J WOODS
• 金额: $ 7.09万
• 依托单位: UNIVERSITY OF GEORGIA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-02-01 至 2012-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361796
• 关键词: Binding Sites; Complex; Data; Funding; Galectin 1; Grant; Maps; Methods; Modeling; National Center for Research Resources; Oligosaccharides; Principal Investigator; Research; Research Infrastructure; Resources; Source; Study models; Testing; United States National Institutes of Health; cost

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Conditions for the practical and general application of the footprinting method are being developed for the galectin-1/LacNAc test case. Crystallographic data exist for this complex enabling it to be used to validate the data interpretation and modeling studies.

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 正在为galectin-1/LacNAc测试案例开发足迹法的实际和一般应用条件。 晶体学数据的存在使其能够用于验证数据解释和建模研究。