HIGH-THROUGHPUT SOLUTION SCATTERING DATA COLLECTION SYSTEM

高通量解决方案散射数据采集系统

• 批准号: 8362096
• 负责人: HIROTSUGU TSURUTA
• 金额: $ 10.97万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-03-01 至 2012-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8362096
• 关键词: Aliquot; Blood capillaries; Cells; Data Collection; Funding; Grant; Liquid substance; National Center for Research Resources; Needles; Principal Investigator; Quartz; Radiation; Research; Research Infrastructure; Resources; Sampling; Solutions; Source; Staging; Syringes; System; Temperature; Translations; United States National Institutes of Health; arm; capillary; cost; instrumentation; structural biology

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. We continue developing the instrumentation for an automated high throughput data collection system for solution x-ray scattering, combining a quartz capillary cell and a motorized sample changer, which comprises a temperature-controlled sample rack in the standard 96-well microplate format and three motorized miniature linear translation stages whose vertical arm holds a syringe needle for sample aliquot selection and delivery. A Hamilton 560 fluid dispenser with two microsyringes and dedicated valves is integrated for pipetting sample aliquots and sending cleaning solutions to the capillary cell.

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 我们继续开发用于溶液X射线散射的自动化高通量数据收集系统的仪器，该系统结合了石英毛细管池和电动进样器，该进样器包括标准96孔微孔板格式的温控样品架和三个电动微型线性平移台，其垂直臂固定用于样品等分试样选择和递送的注射器针头。集成了带有两个微量注射器和专用阀的汉密尔顿560液体分配器，用于移液样品等分试样并将清洁溶液发送到毛细管池。