HIGH-THROUGHPUT SOLUTION SCATTERING DATA COLLECTION SYSTEM

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 我们继续开发用于溶液X射线散射的自动化高通量数据采集系统的仪器，结合了石英毛细管池和电动换样器，该换样器包括一个标准96孔微孔板格式的温控样品架和三个电动微型线性平移工作台，其垂直臂固定着用于样品等分选择和输送的注射针。汉密尔顿560液体分配器带有两个微型注射器和专用阀门，用于进样等分并将清洁溶液送到毛细管池中。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. We continue developing the instrumentation for an automated high throughput data collection system for solution x-ray scattering, combining a quartz capillary cell and a motorized sample changer, which comprises a temperature-controlled sample rack in the standard 96-well microplate format and three motorized miniature linear translation stages whose vertical arm holds a syringe needle for sample aliquot selection and delivery. A Hamilton 560 fluid dispenser with two microsyringes and dedicated valves is integrated for pipetting sample aliquots and sending cleaning solutions to the capillary cell.