PREDICT MULTI-CENTER DTI REPRODUCIBILITY STUDY

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 这是DTI的多中心旅行受试者再现性研究的一部分。这些数据将用于评价扩散张量成像方案的可靠性，该方案将用作PREDICT的一部分，PREDICT是一项亨廷顿病（HD）的多中心（多供应商）DT成像研究。DTI数据将用于评价标量指标的可靠性以及运动神经、眼神经和边缘回路的纤维跟踪。将在爱荷华州招募5名受试者，并将其与油模一起发送至多个中心，在这些中心将使用包括T1、T2和弥散加权图像的方案对其进行成像（见随附PDF）。扫描将于10月19日星期五下午2点至8点进行。在我们研究中心以及其他研究中心收集的图像将被转移到爱荷华州进行评价。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. This is part of a multi-center traveling subject reproducibility study of DTI. The data will be used to evaluate the reliability of a diffusion tensor imaging protocol that will be used as part of a PREDICT, which is a multi-center (multi-vendor) DT imaging study of Huntington's disease (HD). The DTI data will be used to evaluate reliability of scalar metrics as well as fiber tracking of the motor, oculomotor, and limbic circuits. The 5 subjects will be recruited at Iowa and sent with an oil phantom to a number of centers where they will be imaged using a protocol that includes T1, T2, and Diffusion weighted images (see attached PDF). The scans will occur on Friday, October 19th, from 2pm-8pm. The images collected at our site as well as the images from the other sites will be transferred to Iowa for evaluation.