3D TOF ANGIOGRAPHY USING REAL TIME OPTICAL MOTION CORRECTION

使用实时光学运动校正的 3D TOF 血管造影

• 批准号: 8362964
• 负责人: Daniel Kopeinigg
• 金额: $ 1.95万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8362964
• 关键词: Acute; Angiography; Annual Reports; Back; Child; Circle of Willis; Computer software; Data; Detection; Forehead; Funding; Grant; Head; Image; Instruction; Intracranial Hemorrhages; Ischemic Stroke; Magnetic Resonance; Magnetic Resonance Imaging; Methods; Morphologic artifacts; Motion; National Center for Research Resources; Optics; Patients; Pattern; Principal Investigator; Reading; Research; Research Infrastructure; Resources; Running; Scanning; Source; Stream; Technology; Time; United States National Institutes of Health; Update; Visit; abstracting; cost; feeding; healthy volunteer; research study

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Correction of motion artifacts is an ongoing challenge in MRI. Sadly, motion is often worst in patients that are acutely ill and in which time cannot be afforded to repeat failed exams. This is the case, for example, in children or in patients suffering from acute ischemic stroke or intracranial hemorrhages. In these patients 3D Time of Flight (TOF) angiograms are often performed, but their image quality is often technically borderline or even inadequate due to profound patient motion. We proposed an approach in which external pose information is used that allows one to keep the short-TR features of the TOF intact. MATERIALS & METHODS: A MR-compatible camera was mounted on a head coil and combined with a 2D geometric marker, which was placed on the subject's forehead to allow tracking of head motion. The external tracking processor was running a motion detection software which analyzed the camera's video stream and fed the updated pose data back to the scanner's sequencer. This allows one to adjust in quasi-real time the prescribed slab. Experiment: A healthy volunteer underwent three consecutive scans each consisting of a single 7.7cm 3D slab that covers the Circle of Willis whereby for each acquisition instructions were given to perform a specific motion pattern: to remain still, and to perform head motion as much as permitted by the coil. To read about other projects ongoing at the Lucas Center, please visit http://rsl.stanford.edu/ (Lucas Annual Report and ISMRM 2011 Abstracts)

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 运动伪影的校正是 MRI 中持续存在的挑战。遗憾的是，对于重病患者来说，运动往往是最糟糕的 并且在这段时间内不能再重复失败的考试。例如，儿童或患者就是这种情况 患有急性缺血性中风或颅内出血。在这些患者中进行 3D 飞行时间 (TOF) 血管造影 经常进行，但由于患者的深刻理解，其图像质量在技术上常常处于边缘甚至不足。 运动。我们提出了一种使用外部姿态信息的方法，允许保留短 TR 特征 TOF 完好无损。 材料和方法：将 MR 兼容相机安装在头部线圈上，并与 2D 几何模型相结合 标记，放置在受试者的额头上以跟踪头部运动。外部跟踪处理器是 运行运动检测软件，该软件分析摄像机的视频流并将更新的姿势数据反馈回 扫描仪的定序器。这允许人们准实时地调整规定的板。实验：健康志愿者 进行了三次连续扫描，每次扫描均由覆盖威利斯环的单个 7.7 厘米 3D 平板组成 每个采集指令都被赋予执行特定的运动模式：保持静止并执行头部运动 在线圈允许的范围内。 要了解卢卡斯中心正在进行的其他项目，请访问 http://rsl.stanford.edu/（卢卡斯年度报告和 ISMRM 2011 摘要）