LAC REPRESSOR AND MUTANTS IN COMPLEX WITH OPERATOR DNA

LAC 阻遏物和与操纵子 DNA 复合的突变体

• 批准号: 8361689
• 负责人: MITCHELL LEWIS
• 金额: $ 1.1万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361689
• 关键词: Complex; DNA; DNA Binding Domain; DNA-Protein Interaction; Funding; Grant; Lac Repressors; National Center for Research Resources; Principal Investigator; Research; Research Infrastructure; Resources; Source; Structure; Theoretical Studies; United States National Institutes of Health; Variant; cost; mutant; structural biology

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. We aim to solve the structure of the Lac repressor and DNA binding domain mutants in complex with the symmetric operator and symmetric operator variants for use in theoretical studies of protein-DNA interactions.

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