INTERCELLULAR ADHESION PROTEINS

细胞间粘附蛋白

• 批准号: 8361699
• 负责人: LAWRENCE S SHAPIRO
• 金额: $ 1.12万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361699
• 关键词: Adhesions; Adhesives; Cell surface; Cells; Complex; Funding; Grant; National Center for Research Resources; Nervous system structure; Neurons; Pattern; Principal Investigator; Proteins; Research; Research Infrastructure; Resources; Solid; Source; Tissues; United States National Institutes of Health; Work; adhesion receptor; cost; structural biology

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. We are working to structurally characterize the adhesive complexes of cell surface adhesion receptors, which help to assemble cells into the solid tissues of the body. Some adhesion proteins help to define the pattern of connectivity between neurons, and this help "wire" the nervous system.

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心赠款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其他NIH来源。 为子项目列出的总成本可能 表示子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 我们正在努力从结构上表征细胞表面粘附受体的粘附复合物，这有助于将细胞组装成身体的实体组织。一些粘附蛋白有助于确定神经元之间的连接模式，这有助于“连接”神经系统。